Singh Prem, Talawar Ramappa K, Krishna P D V, Varshney Umesh, Vijayan M
Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Dec 1;62(Pt 12):1231-4. doi: 10.1107/S1744309106045805. Epub 2006 Nov 30.
Uracil N-glycosylase is an enzyme which initiates the pathway of uracil-excision repair of DNA. The enzyme from Mycobacterium tuberculosis was co-expressed with a proteinaceous inhibitor from Bacillus subtilis phage and was crystallized in monoclinic space group C2, with unit-cell parameters a = 201.14, b = 64.27, c = 203.68 A, beta = 109.7 degrees. X-ray data from the crystal have been collected for structure analysis.
尿嘧啶N-糖基化酶是一种启动DNA尿嘧啶切除修复途径的酶。来自结核分枝杆菌的这种酶与来自枯草芽孢杆菌噬菌体的一种蛋白质抑制剂共表达,并在单斜晶系空间群C2中结晶,晶胞参数为a = 201.14、b = 64.27、c = 203.68 Å,β = 109.7°。已收集该晶体的X射线数据用于结构分析。