Steven F S, Johnson J
Department of Biochemistry and Molecular Biology, School of Biological Sciences, University of Manchester.
Cytopathology. 1990;1(4):217-22. doi: 10.1111/j.1365-2303.1990.tb00350.x.
Cervical screening is concerned with the search for abnormal epithelial cells in smears prepared from scrapings from the uterine cervix. It is a highly skilled labour intensive operation and automated methods of detecting dyskariotic cells in cervical smears would be helpful. We report a fluorescence method of detecting abnormal cervical cells in smears and biopsies using a probe for guanidinobenzoatase. This approach has the potential for automation.