Steven F S, Johnson J
Department of Biochemistry and Molecular Biology, School of Biological Sciences, University of Manchester.
Cytopathology. 1990;1(4):217-22. doi: 10.1111/j.1365-2303.1990.tb00350.x.
Cervical screening is concerned with the search for abnormal epithelial cells in smears prepared from scrapings from the uterine cervix. It is a highly skilled labour intensive operation and automated methods of detecting dyskariotic cells in cervical smears would be helpful. We report a fluorescence method of detecting abnormal cervical cells in smears and biopsies using a probe for guanidinobenzoatase. This approach has the potential for automation.
宫颈筛查旨在从子宫颈刮片制备的涂片样本中寻找异常上皮细胞。这是一项劳动强度大、技术要求高的操作，因此，能自动检测宫颈涂片中发育异常细胞的方法将大有助益。我们报告了一种利用胍基苯甲酸酶探针，检测涂片和活检样本中异常宫颈细胞的荧光方法。该方法具有自动化的潜力。
