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带状疱疹管理建议。

Recommendations for the management of herpes zoster.

作者信息

Dworkin Robert H, Johnson Robert W, Breuer Judith, Gnann John W, Levin Myron J, Backonja Miroslav, Betts Robert F, Gershon Anne A, Haanpaa Maija L, McKendrick Michael W, Nurmikko Turo J, Oaklander Anne Louise, Oxman Michael N, Pavan-Langston Deborah, Petersen Karin L, Rowbotham Michael C, Schmader Kenneth E, Stacey Brett R, Tyring Stephen K, van Wijck Albert J M, Wallace Mark S, Wassilew Sawko W, Whitley Richard J

机构信息

Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY, 14642, USA.

出版信息

Clin Infect Dis. 2007 Jan 1;44 Suppl 1:S1-26. doi: 10.1086/510206.

Abstract

The objective of this article is to provide evidence-based recommendations for the management of patients with herpes zoster (HZ) that take into account clinical efficacy, adverse effects, impact on quality of life, and costs of treatment. Systematic literature reviews, published randomized clinical trials, existing guidelines, and the authors' clinical and research experience relevant to the management of patients with HZ were reviewed at a consensus meeting. The results of controlled trials and the clinical experience of the authors support the use of acyclovir, brivudin (where available), famciclovir, and valacyclovir as first-line antiviral therapy for the treatment of patients with HZ. Specific recommendations for the use of these medications are provided. In addition, suggestions are made for treatments that, when used in combination with antiviral therapy, may further reduce pain and other complications of HZ.

摘要

本文的目的是提供基于证据的带状疱疹(HZ)患者管理建议,其中考虑到临床疗效、不良反应、对生活质量的影响以及治疗成本。在一次共识会议上,对系统文献综述、已发表的随机临床试验、现有指南以及作者与HZ患者管理相关的临床和研究经验进行了审查。对照试验的结果和作者的临床经验支持使用阿昔洛韦、溴夫定(如可用)、泛昔洛韦和伐昔洛韦作为治疗HZ患者的一线抗病毒疗法。文中提供了这些药物使用的具体建议。此外,还针对与抗病毒疗法联合使用时可能进一步减轻HZ疼痛和其他并发症的治疗方法提出了建议。

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