美味猕猴桃根提取物的抗肿瘤作用研究
[Study on anti-tumor effect of extractions from roots of Actinidia deliciosa].
作者信息
Liang Jie, Wang Xin-sheng, Zhen Han-shen, Zhong Zhen-guo, Zhang Wen-yan, Zhang Wei-wei, Li Wu-lai
机构信息
Faculty of Pharmacy, Guangxi Traditional Chinese Medical University, Guangxi Nanning 530001, China.
出版信息
Zhong Yao Cai. 2007 Oct;30(10):1279-82.
OBJECTIVE
To study the anti-tumor effect of ADEE and ADBE in mice.
METHODS
The models of S180 entity tumor mice and H22 bearing tumor mice were established to observe the effect of ADEE and ADBE on inhibiting S180 entity tumor growth and prolonging life time of H22-mice, and the effect on spleen and thymus index to S180 entity tumor.
RESULTS
Both ADEE and ADBE had ohvious anti-tumor effects to S180-mice (P < 0.05, P < 0.01) and could prolong H22-mice life (P < 0.05, P < 0.01). In certain degree, ADEE and ADBE could improve the immune function of bearing tumor mice.
CONCLUSION
ADEE and ADBE have obvious anti-tumor effect.
目的
研究ADEE和ADBE对小鼠的抗肿瘤作用。
方法
建立S180实体瘤小鼠模型和H22荷瘤小鼠模型，观察ADEE和ADBE对抑制S180实体瘤生长及延长H22小鼠生存期的作用，以及对S180实体瘤小鼠脾和胸腺指数的影响。
结果
ADEE和ADBE对S180小鼠均有明显的抗肿瘤作用（P<0.05，P<0.01），且能延长H22小鼠生存期（P<0.05，P<0.01）。在一定程度上，ADEE和ADBE可提高荷瘤小鼠的免疫功能。
结论
ADEE和ADBE具有明显的抗肿瘤作用。
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