Kozyrev S A, Nikitin V P, Sherstnev V V
Zh Vyssh Nerv Deiat Im I P Pavlova. 1991 Mar-Apr;41(2):323-32.
The role of brain-specific nonhistone proteins of chromatine Np-3.5 in the processes of reproduction of elaborated defensive habit to food was studied in previously learning snails. It was found, that gamma-globulines to Np-3.5 during tens of minutes inhibited behavioural and neuronal reactions elicited by a definite conditioned stimulus--carrot juice, without changing reactions to other conditioned stimulus--apple juice. gamma-globulines to other nonhistone proteins of chromatine did not influence the reproduction of food rejection habits. It was supposed that brain-specific nonhistone proteins of chromatine Np-3.5 were selectively involved in the molecular processes providing for neurophysiological mechanisms of information extraction from the long-term memory.
在先前经过学习的蜗牛中,研究了染色质Np - 3.5的脑特异性非组蛋白在对食物形成的防御习性再现过程中的作用。研究发现,针对Np - 3.5的γ球蛋白在数十分钟内抑制了由特定条件刺激——胡萝卜汁引发的行为和神经元反应,而对其他条件刺激——苹果汁引发的反应没有影响。针对染色质其他非组蛋白的γ球蛋白对食物排斥习性的再现没有影响。据推测,染色质Np - 3.5的脑特异性非组蛋白选择性地参与了从长期记忆中提取信息的神经生理机制的分子过程。