Espinoza A, Hartmann J, Schrader D, Nowakowski H
Klin Wochenschr. 1975 Oct 1;53(19):923-6. doi: 10.1007/BF01468985.
Bilaterally adrenalectomized patients (18) because of Cushing's syndrome were studied. 16 of these 18 persons exhibited fairly high plasma ACTH levels. Distinctly elevated plasma ACTH levels were observed in 6 of them. 5 patients of this group showed an enlarged sella and deep pigmentation of the skin. 4 of the latter group had a mucoid cell adenoma which was removed selectively. After the surgery the ACTH values were found to be within normal range without any significant endocrine dysfunction of the pituitary. A long-term ACTH survey revealed that the ACTH levels remained within the ranges of bilaterally adrenalectomized Cushing patients without concomitant enlargement of the sella or pigmentation.
对因库欣综合征而双侧肾上腺切除的18例患者进行了研究。这18人中的16人血浆促肾上腺皮质激素（ACTH）水平相当高。其中6人血浆ACTH水平明显升高。该组中有5例患者蝶鞍增大且皮肤色素沉着加深。后一组中的4例患有黏液样细胞腺瘤，已被选择性切除。手术后发现促肾上腺皮质激素值在正常范围内，垂体无任何明显的内分泌功能障碍。一项长期促肾上腺皮质激素调查显示，促肾上腺皮质激素水平保持在双侧肾上腺切除的库欣病患者范围内，无蝶鞍增大或色素沉着。
