Schmidtke Klaus, Olbrich Susanne
Center for Geriatric Medicine and Gerontology Freiburg, University Hospital Freiburg, Germany.
Int Psychogeriatr. 2007 Apr;19(2):307-21. doi: 10.1017/S104161020600456X. Epub 2006 Dec 6.
The 12-item Clock Reading Test (CRT) allows a fine-graded assessment of clock-reading ability. It has a strong focus on visuo-spatial processing and requires no executive processing. This study evaluated the reliability, validity, sensitivity and specificity of the CRT for the diagnosis of dementia and visuo-spatial dysfunction.
The CRT, the Clock Drawing Test (CDT) and other tests were applied to groups of 200 subjects with dementia, 105 subjects with mild cognitive impairment (MCI), 20 subjects with focal parietal lesions and 64 elderly control subjects.
The CRT was found to be reliable and sensitive for the detection of cognitive impairment in parietal lesions, Alzheimer-, mixed- and Lewy Body dementia. Normal subjects and patients with MCI, frontotemporal dementia or cerebral small vessel disease showed little or no impairment.
CRT and CDT are clock-processing tests with different demand profiles. They can supplement each other in the neuropsychological diagnosis of dementia and visuo-spatial dysfunction.
12项时钟阅读测试(CRT)能够对时钟阅读能力进行精细分级评估。该测试高度聚焦于视觉空间处理,无需执行功能处理。本研究评估了CRT在诊断痴呆和视觉空间功能障碍方面的信度、效度、敏感性和特异性。
将CRT、时钟绘画测试(CDT)及其他测试应用于200名痴呆患者、105名轻度认知障碍(MCI)患者、20名局灶性顶叶病变患者及64名老年对照受试者。
发现CRT在检测顶叶病变、阿尔茨海默病、混合型和路易体痴呆中的认知障碍方面具有可靠性和敏感性。正常受试者以及MCI、额颞叶痴呆或脑小血管病患者几乎没有或未出现损伤。
CRT和CDT是具有不同需求特征的时钟处理测试。它们在痴呆和视觉空间功能障碍的神经心理学诊断中可相互补充。