Beblo Thomas, Saavedra Anamaria Silva, Mensebach Christoph, Lange Wolfgang, Markowitsch Hans-Joachim, Rau Harald, Woermann Friedrich G, Driessen Martin
Division of Research, Evaluation and Documentation, Clinic of Psychiatry and Psychotherapy Bethel, Ev. Hospital Bielefeld, Remterweg 69-71, 33617 Bielefeld, Germany.
Psychiatry Res. 2006 Dec 7;145(2-3):127-35. doi: 10.1016/j.psychres.2006.01.017. Epub 2006 Oct 30.
For Borderline Personality Disorder (BPD) cognitive and perceptual impairments were reported in some but not all studies. The aim of the present study was to analyze the neuropsychological performance of BPD patients in different domains. Predominant impairments of visual functions and an increased intra-individual variation of test performances within neuropsychological domains were expected. We investigated 22 patients with BPD and a matched sample of 22 healthy control subjects. A comprehensive clinical and neuropsychological test battery was administered. Effect sizes indicate primarily deficits of visual functions such as visual memory (Wechsler Memory Scale-Revised, WMS-R: Visual pair associates and visual reproduction, Complex Figure Test: Recall) and visuo-spatial abilities (Leistungspruefsystem, LPS 9 and 10: Spatial imagination and embedded figures), but also of executive functions (Tower of Hanoi, Trail Making Test-B, semantic and figural fluency, LPS 4: Reasoning). In addition, the intra-individual ranges of neuropsychological test results in BPD patients were increased compared to those of healthy subjects. This finding might be due to a high degree of temporary stress that interferes with effective cognitive processing. Further research is needed to confirm the present results and to control for stress during the test procedure.
对于边缘型人格障碍(BPD),一些但并非所有研究都报告了认知和感知障碍。本研究的目的是分析BPD患者在不同领域的神经心理学表现。预计视觉功能会有主要损害,并且神经心理学领域内测试表现的个体内差异会增加。我们调查了22名BPD患者和22名健康对照受试者的匹配样本。实施了一套全面的临床和神经心理学测试。效应量主要表明视觉功能存在缺陷,如视觉记忆(韦氏记忆量表修订版,WMS-R:视觉配对联想和视觉再现,复杂图形测试:回忆)和视觉空间能力( Leistungspruefsystem,LPS 9和10:空间想象力和镶嵌图形),但执行功能也存在缺陷(河内塔、连线测验B、语义和图形流畅性、LPS 4:推理)。此外,与健康受试者相比,BPD患者神经心理学测试结果的个体内范围有所增加。这一发现可能是由于高度的临时压力干扰了有效的认知处理。需要进一步研究来证实目前的结果,并在测试过程中控制压力。