Tanaka Nobutada, Nakanishi Masayuki, Kusakabe Yoshio, Shiraiwa Katsura, Yabe Saori, Ito Yasutomo, Kitade Yukio, Nakamura Kazuo T
School of Pharmaceutical Sciences, Showa University, Tokyo 142-8555, Japan.
Nucleic Acids Symp Ser (Oxf). 2004(48):281-2. doi: 10.1093/nass/48.1.281.
Structural information of Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase (PfSAHH) has been expected to provide new-type chemotherapeutic agents against malaria. Here we report the crystal structure of PfSAHH. The present structure should provide opportunities to design potent and selective PfSAHH inhibitors.
