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苝标记的碱基识别荧光(BDF)核苷的合成及其荧光性质。

Synthesis of perylene-labeled base-discriminating fluorescent (BDF) nucleoside and its fluorescence properties.

作者信息

Bag Subhendu Sekhar, Saito Yoshio, Hanawa Kazuo, Hayasi Keigo, Kodate Satoshi, Suzuka Isamu, Saito Isao

机构信息

Newcat Institute, School of Engineering, Nihon University, Tamura, Koriyama, Fukushima 963-8642, Japan.

出版信息

Nucleic Acids Symp Ser (Oxf). 2006(50):179-80. doi: 10.1093/nass/nrl089.

Abstract

We have synthesized perylene labeled BDF probe and its photophysical properties were explored. Perylene labeled oligonucleotide probe is capable of detecting cytosine from its target mismatch sequence by enhancement of fluorescence intensity.

摘要

我们合成了苝标记的BDF探针,并对其光物理性质进行了研究。苝标记的寡核苷酸探针能够通过增强荧光强度从其目标错配序列中检测出胞嘧啶。

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