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吖啶酮标记的碱基区分荧光(BDF)核苷的合成与性质

Synthesis and properties of acridone-labeled base-discriminating fluorescent (BDF) nucleosides.

作者信息

Saito Yoshio, Hanawa Kazuo, Bag Subhendu Sekhar, Motegi Kaori, Saito Isao

机构信息

NEWCAT Institue, School of Engineering, Nihon University and SORST, Japan Science and Tecnology Agency, Tamura, Koriyama 963-8642, Japan.

出版信息

Nucleic Acids Symp Ser (Oxf). 2006(50):181-2. doi: 10.1093/nass/nrl090.

DOI:10.1093/nass/nrl090
PMID:17150877
Abstract

We have developed novel acridone-labelled BDF probe which showed its potential in recognizing opposite matched base from its target sequence via enhancement of fiuorescence intensity. This probe emit at a longer wavelength than previously reported pyrene-labelled BDF probe and thus can be used in DNA chip.

摘要

我们开发了新型吖啶酮标记的BDF探针,该探针通过增强荧光强度显示出从其靶序列识别互补匹配碱基的潜力。这种探针的发射波长比先前报道的芘标记的BDF探针更长,因此可用于DNA芯片。

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