Zarei Mojtaba, Johansen-Berg Heidi, Jenkinson Mark, Ciccarelli Olga, Thompson Alan J, Matthews Paul M
Centre for Functional MRI of the Brain, Department of Clinical Neurology, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.
J Magn Reson Imaging. 2007 Jan;25(1):48-54. doi: 10.1002/jmri.20810.
To exploit diffusion imaging tractography to produce a two-dimensional (xy) probabilistic population map of the cortical connections within the human internal capsule (IC).
Diffusion tensor imaging (DTI) was carried out on 11 healthy volunteers. We parceled an axial section of the IC according to its connections to the prefrontal, premotor, primary motor, primary somatosensory, posterior parietal, and occipital cortices using our locally developed probabilistic algorithm.
A consistent topographical organization was generated that was consistent with our anatomical knowledge of the IC. In addition, our study shows that in humans the anterior half of the IC is occupied by the prefrontal cortex.
This map may be of clinical use for correlating neurological deficit with hemispheric lesions, particularly those that affect sensorimotor function.
利用扩散成像纤维束成像技术生成人类内囊(IC)内皮质连接的二维(xy)概率性群体图谱。
对11名健康志愿者进行扩散张量成像(DTI)。我们使用本地开发的概率算法,根据内囊与前额叶、运动前区、初级运动区、初级体感区、顶叶后部和枕叶皮质的连接,将内囊的一个轴向截面进行了划分。
生成了一个与我们对内囊的解剖学知识相一致的一致的地形组织。此外,我们的研究表明,在人类中,内囊的前半部分被前额叶皮质占据。
该图谱可能在临床上用于将神经功能缺损与半球病变相关联,特别是那些影响感觉运动功能的病变。