Habas Christophe, Cabanis Emmanuel Alain
Service de NeuroImagerie, Hôpital des Quinze-Vingts, UPMC Paris 6, 28 rue de Charenton, Paris, France.
Neuroradiology. 2007 Sep;49(9):777-84. doi: 10.1007/s00234-007-0260-y. Epub 2007 Jul 21.
In a previous study using streamlined diffusion tensor imaging (DTI) axonal tracking at 1.5 T, we found that the main afferents to the human red nucleus arise from the sensorimotor and prefrontal cortices. However, the spatial resolution of our data was low and our streamlining DTI algorithm was less powerful than the probabilistic tractography algorithm usually used to define connections between low anisotropic cortical or nuclear areas. Therefore, we reassessed and completed our previous results with trajectories computed with a probabilistic algorithm and with a high-field MRI system.
Afferents to the red nuclei of five volunteers were studied at 3 T using probabilistic DTI axonal tracking.
Trajectories were constantly tracked between the red nucleus and the ipsilateral prefrontal, pericentral, temporal and occipital cortices, and the ipsilateral lentiform and contralateral dentate nuclei. We showed that the dentate nucleus was connected to the mammillary tubercle and, through the contralateral ventral thalamus, to the frontal and prefrontal cortices.
The red nucleus receives extensive projections from the cerebral cortex and has dense subcortical connections to the striopallidal system.
在之前一项使用1.5T简化扩散张量成像（DTI）轴突追踪技术的研究中，我们发现人类红核的主要传入神经源自感觉运动皮层和前额叶皮层。然而，我们数据的空间分辨率较低，并且我们的简化DTI算法不如通常用于定义低各向异性皮层或核区之间连接的概率性纤维束成像算法强大。因此，我们使用概率性算法和高场MRI系统重新评估并完善了我们之前的结果。
使用概率性DTI轴突追踪技术在3T对五名志愿者的红核传入神经进行了研究。
在红核与同侧前额叶、中央周围、颞叶和枕叶皮层，以及同侧豆状核和对侧齿状核之间持续追踪到了纤维束轨迹。我们发现齿状核与乳头结节相连，并通过对侧腹侧丘脑与额叶和前额叶皮层相连。
红核接受来自大脑皮层的广泛投射，并与纹状体苍白球系统有密集的皮层下连接。
