Somani B K, Nabi G, Thorpe P, Hussey J, McClinton S
Department of Urology, Aberdeen Royal Infirmary, Aberdeen, AB25 2WA, UK.
Surgeon. 2006 Dec;4(6):348-52. doi: 10.1016/s1479-666x(06)80110-1.
The aim of this study was to critically appraise the efficacy and complications of Therapeutic Transarterial Embolisation (TAE) in various benign and malignant renal conditions.
The records of all patients who underwent renal embolisation procedures, at a single institution, between March 1992 and March 2004, were reviewed. The patients were identified from hospital records via the procedure coding system and the radiology department procedures book and were analysed retrospectively. Twenty-nine patients were analysed, looking at indications, clinical outcome, complications and long-term results.
Twenty-nine patients underwent 35 embolisation procedures during this period. Fourteen patients with benign diseases underwent 17 embolisation procedures for haematuria or intractable pain. In the haematuria group, selective embolisation was used to treat bleeding post percutaneous nephrolithotomy (PCNL) (n=4), angiomyolipoma (n=2), arteriovenous (AV) malformation (n=l1), renal artery aneurysm (n=1) and renal trauma (n=2). In the renal pain group (n=3), non-selective embolisation was done. Two of these patients had recurrence of pain despite repeat embolisation and subsequently underwent nephrectomy. Fifteen patients with advanced renal malignancy, who were deemed unfit for surgery, underwent 18 embolisation procedures for symptomatic haematuria. Twelve of the 15 patients had successful outcomes with cessation of haematuria. Three patients required repeat embolisation procedures for continuing haematuria with success. There were no major embolisation-related complications. Minor complications were self-limiting and settled with conservative management.
Renal artery embolisation is effective in managing haematuria in benign and malignant renal conditions where indicated, with minor and easily treatable adverse effects
本研究旨在严格评估经动脉栓塞治疗(TAE)在各种良性和恶性肾脏疾病中的疗效及并发症。
回顾了1992年3月至2004年3月期间在单一机构接受肾脏栓塞手术的所有患者的记录。通过手术编码系统和放射科手术记录从医院记录中识别出这些患者,并进行回顾性分析。分析了29例患者,观察其适应证、临床结果、并发症及长期疗效。
在此期间,29例患者接受了35次栓塞手术。14例患有良性疾病的患者因血尿或顽固性疼痛接受了17次栓塞手术。在血尿组中,选择性栓塞用于治疗经皮肾镜取石术后出血(PCNL)(n = 4)、肾血管平滑肌脂肪瘤(n = 2)、动静脉畸形(n = 1)、肾动脉瘤(n = 1)和肾外伤(n = 2)。在肾痛组(n = 3)中,进行了非选择性栓塞。尽管重复栓塞,其中2例患者仍有疼痛复发,随后接受了肾切除术。15例被认为不适合手术的晚期肾恶性肿瘤患者因症状性血尿接受了18次栓塞手术。15例患者中有12例取得了成功,血尿停止。3例患者因持续性血尿需要重复栓塞手术并取得成功。没有与栓塞相关的重大并发症。轻微并发症具有自限性,通过保守治疗得以缓解。
在有指征的良性和恶性肾脏疾病中,肾动脉栓塞治疗血尿有效,且不良反应轻微,易于治疗。