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弹性边界附近冲击波与单个惯性气泡之间的相互作用。

Interaction between shock wave and single inertial bubbles near an elastic boundary.

作者信息

Sankin G N, Zhong P

机构信息

Department of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708, USA.

出版信息

Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Oct;74(4 Pt 2):046304. doi: 10.1103/PhysRevE.74.046304. Epub 2006 Oct 16.

DOI:10.1103/PhysRevE.74.046304
PMID:17155170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1947943/
Abstract

The interaction of laser-generated single inertial bubbles (collapse time = 121 mus) near a silicon rubber membrane with a shock wave (55 MPa in peak pressure and 1.7 mus in compressive pulse duration) is investigated. The interaction leads to directional, forced asymmetric collapse of the bubble with microjet formation toward the surface. Maximum jet penetration into the membrane is produced during the bubble collapse phase with optimal shock wave arrival time and stand-off distance. Such interaction may provide a unique acoustic means for in vivo microinjection, applicable to targeted delivery of macromolecules and gene vectors to biological tissues.

摘要

研究了激光产生的单个惯性气泡（坍缩时间 = 121微秒）在硅橡胶膜附近与冲击波（峰值压力为55兆帕，压缩脉冲持续时间为1.7微秒）的相互作用。这种相互作用导致气泡定向、强制不对称坍缩，并朝着表面形成微射流。在气泡坍缩阶段，当冲击波到达时间和间距距离最佳时，微射流对膜的穿透深度最大。这种相互作用可能为体内微注射提供一种独特的声学手段，适用于将大分子和基因载体靶向递送至生物组织。

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