Department of Mechanical Engineering and Materials Science, Duke University, Box 90300, Durham, North Carolina 27708, USA.
Phys Rev Lett. 2010 Aug 13;105(7):078101. doi: 10.1103/PhysRevLett.105.078101. Epub 2010 Aug 9.
The interaction of laser-generated tandem microbubble (maximum diameter of about 50 μm) with single (rat mammary carcinoma) cells is investigated in a 25-μm liquid layer. Antiphase and coupled oscillation of the tandem microbubble leads to the formation of alternating, directional microjets (with max microstreaming velocity of 10 m/s) and vortices (max vorticity of 350 000 s{-1}) in opposite directions. Localized and directional membrane poration (200 nm to 2 μm in pore size) can be produced by the tandem microbubble in an orientation and proximity-dependent manner, which is absent from a single oscillating microbubble of comparable size and at the same stand-off distance.
在 25μm 的液层中研究了激光产生的串联微泡（最大直径约为 50μm）与单个（大鼠乳腺癌）细胞的相互作用。串联微泡的反相和耦合振荡导致交替的、定向微射流（最大微射流速度为 10m/s）和相反方向的涡旋（最大涡度为 350000s^{-1}）的形成。通过串联微泡可以以定向和接近依赖性的方式产生局部和定向的膜穿孔（孔径为 200nm 至 2μm），而在相同的离轴距离和尺寸相当的单个振荡微泡中则不存在这种情况。
