CD4+/CD25高调节性T细胞的耗竭可能会增强或揭示健康个体中针对凝血因子VIII的T细胞反应。 - Suppr

Suppr

超能文献

Depletion of CD4+/CD25high regulatory T cells may enhance or uncover factor VIII-specific T-cell responses in healthy individuals.

作者信息

Kamaté C, Lenting P J, van den Berg H M, Mutis T

出版信息

J Thromb Haemost. 2007 Mar;5(3):611-3. doi: 10.1111/j.1538-7836.2007.02336.x. Epub 2006 Nov 28.

DOI:10.1111/j.1538-7836.2007.02336.x

PMID:17155960

Abstract

摘要

相似文献

Depletion of CD4+/CD25high regulatory T cells may enhance or uncover factor VIII-specific T-cell responses in healthy individuals.CD4+/CD25高调节性T细胞的耗竭可能会增强或揭示健康个体中针对凝血因子VIII的T细胞反应。

J Thromb Haemost. 2007 Mar;5(3):611-3. doi: 10.1111/j.1538-7836.2007.02336.x. Epub 2006 Nov 28.

Dendritic cells partially abrogate the regulatory activity of CD4+CD25+ T cells present in the human peripheral blood.树突状细胞部分消除了人外周血中存在的CD4+CD25+ T细胞的调节活性。

Int Immunol. 2007 Mar;19(3):227-37. doi: 10.1093/intimm/dxl139. Epub 2007 Feb 7.

Cryopreservation does not alter the frequency of regulatory T cells in peripheral blood mononuclear cells.冷冻保存不会改变外周血单个核细胞中调节性T细胞的频率。

J Immunol Methods. 2010 Feb 28;353(1-2):138-40. doi: 10.1016/j.jim.2009.11.012. Epub 2009 Nov 15.

Acute HIV seroconversion presenting with active tuberculosis and associated with high levels of T-regulatory cells.急性 HIV 血清转换伴发活动性结核病，并与高水平 T 调节细胞相关。

Viral Immunol. 2011 Aug;24(4):347-9. doi: 10.1089/vim.2010.0101. Epub 2011 Jul 20.

Generation of highly suppressive adaptive CD8(+)CD25(+)FOXP3(+) regulatory T cells by continuous antigen stimulation.通过持续抗原刺激产生高度抑制性的适应性CD8(+)CD25(+)FOXP3(+)调节性T细胞。

Eur J Immunol. 2008 Mar;38(3):640-6. doi: 10.1002/eji.200737529.

In vitro expansion of CD4+CD25highFOXP3+CD127low/- regulatory T cells from peripheral blood lymphocytes of healthy Mycobacterium tuberculosis-infected humans.从健康结核分枝杆菌感染人类的外周血淋巴细胞中体外扩增CD4+CD25高表达FOXP3+CD127低表达/阴性调节性T细胞

Microbes Infect. 2007 Sep;9(11):1325-32. doi: 10.1016/j.micinf.2007.06.004. Epub 2007 Jun 30.

Systemic immune tuning in renal cell carcinoma: favorable prognostic impact of TGF-β1 mRNA expression in peripheral blood mononuclear cells.系统性免疫调节在肾细胞癌中的作用：外周血单个核细胞中 TGF-β1 mRNA 表达的有利预后影响。

J Immunother. 2011 Jan;34(1):113-9. doi: 10.1097/CJI.0b013e3181fb6580.

Immune regulation in Chandipura virus infection: characterization of CD4+ T regulatory cells from infected mice.钱德拉普尔病毒感染中的免疫调节：从感染小鼠中鉴定 CD4+T 调节性细胞。

Virol J. 2011 May 25;8:259. doi: 10.1186/1743-422X-8-259.

The expression profile of functional regulatory T cells, CD4+CD25high+/forkhead box protein P3+, in patients with ulcerative colitis during active and quiescent disease.活动期和静止期溃疡性结肠炎患者中功能性调节性T细胞（CD4+CD25high+/叉头框蛋白P3+）的表达谱

Clin Exp Immunol. 2009 May;156(2):320-7. doi: 10.1111/j.1365-2249.2009.03904.x. Epub 2009 Mar 9.

CD4+ CD25+ regulatory T cells in human pregnancy: development of a Treg-MLC-ELISPOT suppression assay and indications of paternal specific Tregs.人类妊娠中的CD4+ CD25+调节性T细胞：Treg-MLC-ELISPOT抑制试验的开发及父源特异性Tregs的指征

Immunology. 2007 Apr;120(4):456-66. doi: 10.1111/j.1365-2567.2006.02529.x. Epub 2007 Jan 11.

引用本文的文献

The self-reactive FVIII T cell repertoire in healthy individuals relies on a short set of epitopes and public clonotypes.健康个体中自身反应性 FVIII T 细胞库依赖于一小部分表位和公共克隆型。

Front Immunol. 2024 Mar 6;15:1345195. doi: 10.3389/fimmu.2024.1345195. eCollection 2024.

Anti-FVIII antibodies in Black and White hemophilia A subjects: do F8 haplotypes play a role?黑人和白人血友病 A 患者中的抗 FVIII 抗体：F8 单倍型是否起作用？

Blood Adv. 2023 Sep 12;7(17):4983-4998. doi: 10.1182/bloodadvances.2021004909.

Development of a novel fully functional coagulation factor VIII with reduced immunogenicity utilizing an in silico prediction and deimmunization approach.利用计算机预测和免疫原性降低技术开发新型具有低免疫原性的完全功能凝血因子 VIII。

J Thromb Haemost. 2021 Sep;19(9):2161-2170. doi: 10.1111/jth.15413. Epub 2021 Jun 30.

Tolerating Factor VIII: Recent Progress.耐受因子 VIII：最新进展。

Front Immunol. 2020 Jan 10;10:2991. doi: 10.3389/fimmu.2019.02991. eCollection 2019.

Anti-Drug Antibodies: Emerging Approaches to Predict, Reduce or Reverse Biotherapeutic Immunogenicity.抗药物抗体：预测、降低或逆转生物治疗性免疫原性的新方法

Antibodies (Basel). 2018 May 31;7(2):19. doi: 10.3390/antib7020019.

Pathogenic immune response to therapeutic factor VIII: exacerbated response or failed induction of tolerance?治疗性因子 VIII 的致病性免疫反应：加剧的反应还是耐受诱导失败？

Haematologica. 2019 Feb;104(2):236-244. doi: 10.3324/haematol.2018.206383. Epub 2018 Dec 4.

Activation of CD4 and CD8 T cell receptors and regulatory T cells in response to human proteins.响应人类蛋白质时CD4和CD8 T细胞受体及调节性T细胞的激活。

PeerJ. 2018 Mar 9;6:e4462. doi: 10.7717/peerj.4462. eCollection 2018.

Achievements, challenges and unmet needs for haemophilia patients with inhibitors: Report from a symposium in Paris, France on 20 November 2014.血友病抑制物患者的成就、挑战与未满足需求：2014年11月20日于法国巴黎召开的研讨会报告

Haemophilia. 2016 Jan;22 Suppl 1(Suppl 1):1-24. doi: 10.1111/hae.12860.

HLA-DR-restricted T-cell responses to factor VIII epitopes in a mild haemophilia A family with missense substitution A2201P.在一个具有错义突变 A2201P 的轻度血友病 A 家族中，针对因子 VIII 表位的 HLA-DR 限制性 T 细胞反应。

Haemophilia. 2010 May;16(102):44-55. doi: 10.1111/j.1365-2516.2008.01905.x.

Role of regulatory T cells in tolerance to coagulation factors.调节性T细胞在对凝血因子的耐受性中的作用。

J Thromb Haemost. 2009 Jul;7 Suppl 1(Suppl 1):88-91. doi: 10.1111/j.1538-7836.2009.03417.x.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验