Volpes R, van den Oord J J, Desmet V J
Department of Pathology, University Hospital Sint-Rafaël, Catholic University of Leuven, Belgium.
APMIS Suppl. 1991;23:53-67.
Cell-mediated immune reactions occurring in liver diseases involve infiltration of inflammatory cells into the hepatic parenchyma. Almost nothing is known about cellular and molecular mechanisms regulating this leukocyte traffic during the afferent and efferent arms of the hepatic immune response. This overview emphasizes that various liver parenchymal cells appear to participate actively in the development of the inflammatory response.