Fan P C, Chao D, Lee K M, Chan C H, Liu H Y
Department of Parasitology, National Yang-ming Medical College, Taipei, Taiwan, R.O.C.
Zhonghua Yi Xue Za Zhi (Taipei). 1991 Jul;48(1):13-9.
In order to evaluate the effectiveness of 1% gamma-BHC emulsion against head louse infestation, 1,527 school children were examined using observation by ocular and combing methods were used and infested children were treated with three regimes of 1% gamma-BHC emulsion. An overall infestation rate of 40% was found. The infestation rate was highest in Tung-Kuang Primary School (59%) and lowest in Chien-Hua Primary Schools (7%). The rate was highest among school children grade 2 (45%) and lowest in grade 3 (35%). The rate of girls (65%) was much higher than that of boys (9%). A total of 443 lice were collected from 78 infested school girls: 56 males, 59 females, and 328 nymph. The average number of head lice in each infested girl was 5.7. Follow-up examination was conducted one week after treatment. The cure rates for dosages of 10.0 ml, 5.0 ml, and 2.5 ml 1% gamma-BHC emulsion were 96%, 88%, 68% for girls and 100%, 92%, and 33% for boys, respectively. Only mild and transient itching and burn sensation of scalp were reported by a few children. The overall infestation rate 5 months (April-September 1981) after treatment was 23% (286/1,245). The rate of girls decreased from 65% to 40% and that of boys from 9% to 3%. Results of the present study indicates that 1% gamma-BHC emulsion is an effective pediculicide at a dosage of 5 ml or 10 ml. However, the overall infestation rate remained high (23%) 5 months after treatment. These findings suggest that treatment of head louse infestation must be conducted continuously.
为评估1%六六六乳剂治疗头虱感染的效果，对1527名学童进行了检查，采用肉眼观察和梳篦法，对感染的儿童采用三种方案的1%六六六乳剂进行治疗。总体感染率为40%。感染率在东光小学最高（59%），在建华小学最低（7%）。二年级学童的感染率最高（45%），三年级最低（35%）。女孩的感染率（65%）远高于男孩（9%）。从78名受感染的女学童身上共收集到443只虱子：56只为雄虱，59只为雌虱，328只为若虫。每名受感染女孩身上头虱的平均数量为5.7只。治疗一周后进行了随访检查。1%六六六乳剂剂量为10.0毫升、5.0毫升和2.5毫升时，女孩的治愈率分别为96%、88%、68%，男孩的治愈率分别为100%、92%和33%。只有少数儿童报告有轻微且短暂的头皮瘙痒和烧灼感。治疗后5个月（1981年4月至9月）的总体感染率为23%（286/1245）。女孩的感染率从65%降至40%，男孩的感染率从9%降至3%。本研究结果表明，1%六六六乳剂剂量为5毫升或10毫升时是一种有效的灭虱剂。然而，治疗后5个月总体感染率仍很高（23%）。这些发现表明，头虱感染的治疗必须持续进行。
