Manáková Eva, Hubicková-Heringová Lucie, Jelínek Richard
3rd Faculty of Medicine, Department of Histology and Embryology, Charles University, Prague, Czech Republic.
Neuro Endocrinol Lett. 2006 Dec;27 Suppl 2:74-7.
Care, treatment and follow-up in psychiatric and epileptic pregnant women were compared with women inquiring Czech Teratology Information Service (CZTIS) due to other exposure to drugs during pregnancy.
Data were collected by CZTIS, member of European Network of Teratology Information Services from 1996. Exposed groups were compared with pregnant women exposed to drugs which were not classified as major teratogens or hyperthermia. Groups do not vary in age, reproductive history and other parameters.
We observed higher frequency of miscarriage and voluntary termination of pregnancy in the group of psychiatric patients. The number of malformation in prospective follow-up cases was lower than in control group.
Chronic diseases as epilepsy or psychiatric disorders have to be treated during pregnancy. Women should obtain accurate information about possible risk before pregnancy. Co-operation is needed in these cases. Physicians should keep in mind that appropriate information is to be given to the patient according to her disease, education and comprehension of the problem. If there is any doubt they should organize help for their patients.
将患有精神疾病和癫痫的孕妇的护理、治疗及随访情况与因孕期接触其他药物而咨询捷克致畸信息服务中心（CZTIS）的女性进行比较。
数据由欧洲致畸信息服务网络成员CZTIS自1996年起收集。将暴露组与暴露于未被归类为主要致畸剂或高热的药物的孕妇进行比较。各组在年龄、生育史及其他参数方面无差异。
我们观察到精神疾病患者组中流产和自愿终止妊娠的发生率较高。前瞻性随访病例中的畸形数量低于对照组。
癫痫或精神疾病等慢性病在孕期必须进行治疗。女性在怀孕前应获取有关可能风险的准确信息。在这些情况下需要合作。医生应牢记，应根据患者的疾病、教育程度和对问题的理解向其提供适当信息。如有任何疑问，他们应为患者组织帮助。
