Elwakil Tarek F
National Institute of Laser Enhanced Sciences (NILES), Cairo University, Cairo, Egypt.
Lasers Med Sci. 2007 Mar;22(1):53-9. doi: 10.1007/s10103-006-0423-9. Epub 2006 Dec 12.
There is no method of treatment that has been proven to accelerate the rate of tendon healing or to improve the quality of the regenerating tendon. Low level laser photostimulation has gained a considerable attention for enhancing tissue repair in a wide spectrum of applications. However, there is controversy regarding the effectiveness of laser photostimulation for improvement of the healing process of surgically repaired tendons. Accordingly, the present study was conducted to evaluate the role of helium-neon (He-Ne) laser photostimulation on the process of healing of surgically repaired Achilles tendons. Thirty unilateral Achilles tendons of 30 Raex rabbits were transected and immediately repaired. Operated Achilles tendons were randomly divided into two equal groups. Tendons at group A were subjected to He-Ne laser (632.8 nm) photostimulation, while tendons at group B served as a control group. Two weeks later, the repaired Achilles tendons were histopathologically and biomechanically evaluated. The histopathological findings suggest the favorable qualitative pattern of the newly synthesized collagen of the regenerating tendons after He-Ne laser photostimulation. The biomechanical results support the same favorable findings from the functional point of view as denoted by the better biomechanical properties of the regenerating tendons after He-Ne laser photostimulation with statistical significance (p <or= 0.01) at most of the biomechanical parameters. He-Ne laser photostimulation reported a great value after surgical repair of ruptured and injured tendons for a better functional outcome. It could be applied safely and effectively in humans, especially with respect to the proposed long-term clinical outcome.
目前尚无已被证实能加速肌腱愈合速度或改善再生肌腱质量的治疗方法。低强度激光光刺激在广泛的应用中促进组织修复方面受到了相当大的关注。然而,关于激光光刺激对手术修复肌腱愈合过程的有效性存在争议。因此,本研究旨在评估氦氖(He-Ne)激光光刺激对手术修复的跟腱愈合过程的作用。对30只新西兰兔的30条单侧跟腱进行横断并立即修复。将手术修复的跟腱随机分为两组,每组数量相等。A组的肌腱接受He-Ne激光(632.8 nm)光刺激,而B组的肌腱作为对照组。两周后,对修复后的跟腱进行组织病理学和生物力学评估。组织病理学结果表明,He-Ne激光光刺激后再生肌腱新合成的胶原蛋白具有良好的定性模式。生物力学结果从功能角度支持了相同的有利发现,即He-Ne激光光刺激后再生肌腱具有更好的生物力学性能,在大多数生物力学参数上具有统计学意义(p≤0.01)。He-Ne激光光刺激在手术修复断裂和损伤的肌腱后显示出巨大价值,可实现更好的功能结果。它可以安全有效地应用于人类,特别是考虑到所提出的长期临床结果。