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血管痉挛的神经介入治疗

Neurointerventional treatment of vasospasm.

作者信息

Brisman Jonathan L, Eskridge Joseph M, Newell David W

机构信息

Department of Cerebrovascular and Endovascular Neurosurgery, New Jersey Neuroscience Institute, Edison, NJ 08818, USA.

出版信息

Neurol Res. 2006 Oct;28(7):769-76. doi: 10.1179/016164106X152043.

Abstract

OBJECTIVES

To review the historical development and current status of endovascular techniques used in the treatment of symptomatic vasospasm following aneurysmal subarachnoid hemorrhage.

METHODS

This article summarizes the relevant literature on neurointerventional therapy for vasospasm, namely instillation of intraarterial medication (papaverine, nicardipine, verapamil) and transluminal balloon angioplasty. The authors synthesize the available literature with their own experience using the various endovascular modalities to treat vasospasm at high volume cerebrovascular centers.

TECHNIQUE

Indications for the use of neurointerventional therapy as well as a summary of the technique for transluminal angioplasty to treat vasospasm as employed by the authors is described.

DISCUSSION

Neurointerventional treatment of vasospasm following aneurysmal hemorrhage has been proven to be a safe and successful technique for those patients suffering symptomatic vasospasm refractory to medical management. The techniques contunue to undergo refinement as endovascular technology advances. We currently favor the use of balloon angioplasty over intraarterial antispasmotics due to the increased durability and long-lasting effects of the former and lower risk profile.

摘要

目的

回顾用于治疗动脉瘤性蛛网膜下腔出血后症状性血管痉挛的血管内技术的历史发展和现状。

方法

本文总结了有关血管痉挛神经介入治疗的相关文献,即动脉内药物灌注(罂粟碱、尼卡地平、维拉帕米)和经腔球囊血管成形术。作者将现有文献与他们自己在大容量脑血管中心使用各种血管内方法治疗血管痉挛的经验相结合。

技术

描述了使用神经介入治疗的适应症以及作者采用的经腔血管成形术治疗血管痉挛的技术总结。

讨论

对于那些药物治疗难以控制症状性血管痉挛的患者,动脉瘤性出血后血管痉挛的神经介入治疗已被证明是一种安全且成功的技术。随着血管内技术的进步,这些技术不断得到改进。由于球囊血管成形术具有更高的耐久性和长效效果以及更低的风险,我们目前更倾向于使用球囊血管成形术而非动脉内抗痉挛药物。

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