Mukherjee B, Shivakumar T
Department of Otorhinolaryngology, Command Hospital Air Force, Bangalore, India.
J Laryngol Otol. 2007 Apr;121(4):395-7. doi: 10.1017/S0022215106005512. Epub 2006 Dec 14.
We report a case of bilateral profound unremitting sensorineural hearing loss, in a 44-year-old male patient occurring after ingestion of sildenafil citrate 50 mg/day for 15 days. Audiological evaluation documented the findings. Sildenafil is an effective oral treatment for erectile dysfunction syndrome. It is being used and abused by many people as availability is easy and it can even be bought over the internet. Many patients are unaware of the harmful effects of sildenafil and take the drug without medical supervision. We could not find any previously reported cases of sildenafil induced hearing loss and to the best of our knowledge, this is the first case report of sildenafil induced sensorineural hearing loss in the world literature.
我们报告一例44岁男性患者，在每天服用50毫克枸橼酸西地那非15天后出现双侧严重且持续性感音神经性听力损失。听力学评估记录了这些发现。西地那非是治疗勃起功能障碍综合征的一种有效口服药物。由于其容易获取甚至可以在网上买到，正被许多人使用和滥用。许多患者并未意识到西地那非的有害影响，在没有医学监督的情况下服用该药物。我们未发现任何先前报道的西地那非所致听力损失病例，据我们所知，这是世界文献中首例西地那非所致感音神经性听力损失的病例报告。
