尼日利亚儿童心力衰竭的患病率、病因及死亡率：一项系统评价与荟萃分析

Prevalence, Etiology, and Fatality Rates of Childhood Heart Failure in Nigeria: A Systematic Review and Meta-analysis.

作者信息

Abdulkadir Mohammed Baba, Ibraheem Rasheedat Mobolaji, Issa Amudalat, Suberu Habibat Dirisu, Owolabi Bilkis Iyabo, Alabi Kayode

机构信息

Department of Paediatrics, University of Ilorin/University of Ilorin Teaching Hospital, Ilorin, Kwara State, Nigeria.

Children Specialist Hospital, Ilorin, Kwara State, Nigeria.

出版信息

Int J Health Sci (Qassim). 2023 Jan-Feb;17(1):53-60.

PMID:36704492

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9832908/

Abstract

OBJECTIVES

The objectives of the study were to describe the burden, etiology, and fatality rates of heart failure in Nigerian children.

METHODS

We searched PubMed database, Google scholar, TRIP database, EMBASE, African Index Medicus, and reference lists of selected articles for studies on burden, etiology, and fatality rates of heart failure in children in Nigeria published from 1977 to 2016. Two researchers reviewed the papers independently. Ten studies were selected that included 14,921 children and 1353 with heart failure.

RESULTS

The overall prevalence of heart failure using all the studies reviewed was 8.3% (95% CI: 4.9-12.6). The prevalence was 13.4% (95% CI: 10.9-16.3) in studies that excluded neonates and 4.5% (95% CI: 2.8-6.5) in studies that included neonates. The most common causes of heart failure were severe anemia (38.9%, 95% CI: 30.0-49.4), respiratory tract infections (32.4%, 95% CI: 25.5-39.7), congenital heart disease (8.4%, 95% CI: 6.8-10.2), and sepsis (7.6%, 95% CI: 3.0-14.0). The overall fatality rate was 16.0% (95% CI: 9.0 - 24.6) and was higher in studies that include neonates.

CONCLUSION

Heart failure is common in children hospitalized in Nigeria. Its etiology is largely from non-cardiac conditions associated with severe hypoxia and mortality rates are high in children in Nigeria.

摘要

目的

本研究的目的是描述尼日利亚儿童心力衰竭的负担、病因和死亡率。

方法

我们检索了PubMed数据库、谷歌学术、TRIP数据库、EMBASE、非洲医学索引以及所选文章的参考文献列表，以查找1977年至2016年发表的关于尼日利亚儿童心力衰竭负担、病因和死亡率的研究。两名研究人员独立审查这些论文。选择了10项研究，其中包括14921名儿童，1353名患有心力衰竭。

结果

综合所有纳入研究，心力衰竭的总体患病率为8.3%（95%置信区间：4.9 - 12.6）。排除新生儿的研究中患病率为13.4%（95%置信区间：10.9 - 16.3），纳入新生儿的研究中患病率为4.5%（95%置信区间：2.8 - 6.5）。心力衰竭最常见的病因是重度贫血（38.9%，95%置信区间：30.0 - 49.4）、呼吸道感染（32.4%，95%置信区间：25.5 - 39.7）、先天性心脏病（8.4%，95%置信区间：6.8 - 10.2）和败血症（7.6%，95%置信区间：3.0 - 14.0）。总体死亡率为16.0%（95%置信区间：9.0 - 24.6），在纳入新生儿的研究中更高。