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Pralidoxime for organophosphate poisoning.

作者信息

Eyer Peter, Buckley Nicholas

机构信息

Walther-Straub-Institute of Pharmacology and Toxicology, University of Munich, Munich D-80336, Germany.

出版信息

Lancet. 2006 Dec 16;368(9553):2110-1. doi: 10.1016/S0140-6736(06)69843-7.

DOI:10.1016/S0140-6736(06)69843-7
PMID:17174692
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1978066/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c5a/2824136/8d8c853f5a19/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c5a/2824136/8d8c853f5a19/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c5a/2824136/8d8c853f5a19/gr1.jpg

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Pralidoxime for organophosphate poisoning.用于有机磷中毒的解磷定
Lancet. 2006 Dec 16;368(9553):2110-1. doi: 10.1016/S0140-6736(06)69843-7.
2
Use of continuous infusion of pralidoxime for treatment of organophosphate poisoning in children.持续输注氯解磷定用于治疗儿童有机磷中毒。
J Pediatr. 1990 Apr;116(4):658-61. doi: 10.1016/s0022-3476(05)81622-1.
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High-dose pralidoxime for organophosphorus poisoning.高剂量解磷定用于有机磷中毒
Lancet. 2007 Apr 28;369(9571):1425. doi: 10.1016/S0140-6736(07)60657-6.
4
[Is PAM an effective antidote for organophosphate poisoning? There is no evidence that PAM is effective in acute organophosphorus poisoning].解磷定是有机磷中毒的有效解毒剂吗？没有证据表明解磷定对急性有机磷中毒有效。
Chudoku Kenkyu. 2010 Mar;23(1):36-40.
5
High-dose pralidoxime for organophosphorus poisoning.高剂量解磷定用于有机磷中毒
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High dose atropine in organophosphorus poisoning.大剂量阿托品用于有机磷中毒。
Postgrad Med J. 1990 Oct;66(780):878. doi: 10.1136/pgmj.66.780.878.
7
[Is PAM an effective antidote for organophosphate poisoning? Pros: PAM (pralidoxime) is effective for acute poisoning of organophosphorus].解磷定是有机磷中毒的有效解毒剂吗？优点：解磷定（派姆）对急性有机磷中毒有效。
Chudoku Kenkyu. 2010 Mar;23(1):31-5.
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Are Oximes Still Indicated for Acute Organophosphorus Insecticide Self-Poisoning?肟类药物仍适用于急性有机磷杀虫剂自服中毒吗？
J Med Toxicol. 2018 Mar;14(1):1-2. doi: 10.1007/s13181-018-0651-y. Epub 2018 Jan 31.
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Does pralidoxime affect outcome of management in acute organophosphorus poisoning?解磷定对急性有机磷中毒的治疗效果有影响吗？
Lancet. 1992 May 9;339(8802):1136-8. doi: 10.1016/0140-6736(92)90733-j.
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Pralidoxime for reducing nicotinic cholinergic morbidity in organophosphate poisoning.用于降低有机磷中毒中烟碱样胆碱能发病率的解磷定
J Assoc Physicians India. 1998 Jul;46(7):668.

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Recent advancements in non-enzymatic electrochemical sensor development for the detection of organophosphorus pesticides in food and environment.用于检测食品和环境中有机磷农药的非酶电化学传感器开发的最新进展。
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本文引用的文献

1
Continuous pralidoxime infusion versus repeated bolus injection to treat organophosphorus pesticide poisoning: a randomised controlled trial.持续输注解磷定与重复推注治疗有机磷农药中毒的随机对照试验
Lancet. 2006 Dec 16;368(9553):2136-41. doi: 10.1016/S0140-6736(06)69862-0.
2
Respiratory failure in acute organophosphorus pesticide self-poisoning.急性有机磷农药自服中毒所致呼吸衰竭
QJM. 2006 Aug;99(8):513-22. doi: 10.1093/qjmed/hcl065. Epub 2006 Jul 22.
3
Organophosphorus poisoning: a study on the effectiveness of therapy with oximes.
阳离子可交换的氯解磷定@生物金属有机框架-1用于治疗动物神经性毒剂中毒和芥子气皮肤中毒
ACS Omega. 2022 Aug 25;7(35):30720-30729. doi: 10.1021/acsomega.2c01240. eCollection 2022 Sep 6.
4
Acute Poisonings at a Regional Referral Hospital in Western Kenya.肯尼亚西部一家地区转诊医院的急性中毒情况
Trop Med Infect Dis. 2018 Sep 3;3(3):96. doi: 10.3390/tropicalmed3030096.
5
Organophosphorus poisoning (acute).有机磷中毒（急性）
BMJ Clin Evid. 2011 May 17;2011:2102.
6
Pralidoxime in acute organophosphorus insecticide poisoning--a randomised controlled trial.急性有机磷杀虫剂中毒时使用解磷定的随机对照试验
PLoS Med. 2009 Jun 30;6(6):e1000104. doi: 10.1371/journal.pmed.1000104.
7
Organophosphorus poisoning (acute).有机磷中毒（急性）
BMJ Clin Evid. 2007 Mar 1;2007:2102.
8
Management of acute organophosphorus pesticide poisoning.急性有机磷农药中毒的管理
Lancet. 2008 Feb 16;371(9612):597-607. doi: 10.1016/S0140-6736(07)61202-1.
有机磷中毒：肟类药物治疗效果的研究
J Assoc Physicians India. 2006 Mar;54:250-1.
4
Differences between organophosphorus insecticides in human self-poisoning: a prospective cohort study.有机磷杀虫剂在人类自我中毒中的差异：一项前瞻性队列研究。
Lancet. 2005;366(9495):1452-9. doi: 10.1016/S0140-6736(05)67598-8.
5
Overcoming apathy in research on organophosphate poisoning.克服有机磷中毒研究中的冷漠态度。
BMJ. 2004 Nov 20;329(7476):1231-3. doi: 10.1136/bmj.329.7476.1231.
6
The role of oximes in the management of organophosphorus pesticide poisoning.肟类化合物在有机磷农药中毒治疗中的作用。
Toxicol Rev. 2003;22(3):165-90. doi: 10.2165/00139709-200322030-00004.
7
Generation of allocation sequences in randomised trials: chance, not choice.随机试验中分配序列的产生：靠的是机遇，而非选择。
Lancet. 2002 Feb 9;359(9305):515-9. doi: 10.1016/S0140-6736(02)07683-3.
8
Patterns and problems of deliberate self-poisoning in the developing world.发展中国家蓄意自我中毒的模式与问题。
QJM. 2000 Nov;93(11):715-31. doi: 10.1093/qjmed/93.11.715.
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Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials.偏倚的实证证据。与对照试验中治疗效果估计相关的方法学质量维度。
JAMA. 1995 Feb 1;273(5):408-12. doi: 10.1001/jama.273.5.408.