Carpenter T E, Snipes K P, Kasten R W, Hird D W, Hirsh D C
Department of Epidemiology and Preventive Medicine, School of Veterinary Medicine, University of California, Davis 95616.
Am J Vet Res. 1991 Aug;52(8):1345-9.
Pasteurella multocida isolated from turkeys during an outbreak of fowl cholera was characterized by serotype and heterogeneity of genes encoding rRNA (ribotype) to investigate the epidemiology of the organism. Isolates were collected between October 1985 and July 1986. The M9 or Clemson University fowl cholera vaccine-like strain was detected in 17% of the flocks with fowl cholera. One particular strain, isolated only from breeder flocks, was recovered from 7 of the 10 breeder flocks examined in this study. Intracompany transmission appeared to be common, implying a failure in biosecurity. Circumstantial evidence indicated that in the field; the incubation period of P multocida in a turkey flock may be between 2 to 7 weeks. Wildlife did not appear to be an important reservoir of P multocida for turkeys during this study period. Ribotyping results tended to discount several of the possible interflock transmissions, as suggested by examination of serotyping results alone; however, serotyping in combination with ribotyping proved helpful in understanding the epidemiology of P multocida in turkeys.
从爆发禽霍乱的火鸡中分离出多杀性巴氏杆菌，通过血清型和编码rRNA的基因异质性（核糖体分型）对其进行特征分析，以研究该病原体的流行病学。分离株于1985年10月至1986年7月期间收集。在17%患有禽霍乱的鸡群中检测到M9或克莱姆森大学禽霍乱疫苗样菌株。在本研究中检查的10个种鸡群中的7个中，分离出一种仅从种鸡群中分离出的特定菌株。公司内部传播似乎很常见，这意味着生物安全措施存在漏洞。间接证据表明，在田间，多杀性巴氏杆菌在火鸡群中的潜伏期可能在2至7周之间。在本研究期间，野生动物似乎不是火鸡多杀性巴氏杆菌的重要储存宿主。核糖体分型结果倾向于否定仅通过血清分型结果所暗示的几种可能的鸡群间传播；然而，血清分型与核糖体分型相结合被证明有助于了解火鸡多杀性巴氏杆菌的流行病学。
