乙胺丁醇毒性导致的异常多焦视网膜电图（mfERG）
Abnormal multifocal electroretinogram (mfERG) in ethambutol toxicity.
作者信息
Kardon Randy H, Morrisey Mary C, Lee Andrew G
机构信息
Department of Ophthalmology, The University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA.
出版信息
Semin Ophthalmol. 2006 Oct-Dec;21(4):215-22. doi: 10.1080/08820530600987454.
OBJECTIVE
To report the abnormal multifocal electroretinogram (mfERG) findings in two cases of presumed ethambutol toxicity.
DESIGN
Retrospective observational case series.
PARTICIPANTS
Two patients with ethambutol toxicity and visual loss.
TESTING
Multifocal electroretinography.
MAIN OUTCOME MEASURE
Waveform measurements on multifocal electroretinography.
RESULTS
Two patients with bilateral visual loss due to ethambutol toxicity underwent mfERG testing that disclosed both diffuse and central field loss compatible with retinal dysfunction as a contributing mechanism to the visual field loss.
CONCLUSION
Ethambutol toxicity affects not only the optic nerve but probably other retinal elements based upon abnormal mfERG findings.
目的
报告两例疑似乙胺丁醇毒性病例的异常多焦视网膜电图（mfERG）检查结果。
设计
回顾性观察病例系列。
参与者
两名患有乙胺丁醇毒性和视力丧失的患者。
检测
多焦视网膜电图检查。
主要观察指标
多焦视网膜电图的波形测量。
结果
两名因乙胺丁醇毒性导致双侧视力丧失的患者接受了mfERG检查，结果显示弥漫性和中心视野丧失，这与视网膜功能障碍相符，提示视网膜功能障碍是视野丧失的一个促成机制。
结论
基于异常的mfERG检查结果，乙胺丁醇毒性不仅影响视神经，还可能影响其他视网膜成分。
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