Kopec Jacek A, Rahman M Mushfiqur, Berthelot Jean-Marie, Le Petit Christel, Aghajanian Jaafar, Sayre Eric C, Cibere Jolanda, Anis Aslam H, Badley Elizabeth M
Department of Health Care and Epidemiology, University of British Columbia, Vancouver, BC, Canada.
J Rheumatol. 2007 Feb;34(2):386-93. Epub 2006 Dec 15.
Osteoarthritis (OA) is a highly prevalent and often disabling disease. Data on the incidence of OA in the general population are limited. Our objectives were (1) to estimate OA prevalence and incidence rates by age and sex in a geographically defined population of 4 million people [British Columbia (BC), Canada] using an administrative database; and (2) to determine the effects of different administrative definitions of OA and observation (run-in) time on such estimates.
We used data on all visits to health professionals and hospital admissions covered by the Medical Services Plan (MSP) of BC for the fiscal years 1991-92 through 2000-01. OA was defined based on International Classification of Diseases, 9th Revision, diagnostic codes required for administrative purposes.
The overall prevalence of OA in 2001 was 10.8%: 8.9% in men and 12.6% in women. Prevalence was higher in women in all age groups. By age 70-74 years, about one-third of men and 40% of women had OA. Incidence rates in 2000-01 were 11.7 per 1000 person-years in the total population, 10.0 in men and 13.4 in women. Rates increased linearly with age between 50 and 80 years. Both prevalence and incidence depended strongly on the definition of OA and the run-in period.
Prevalence of physician-diagnosed OA in BC was slightly lower than self-reported prevalence of arthritis in population surveys. Routinely collected administrative data could be a valuable source of information for OA surveillance, but more research is needed on the validity of OA diagnosis in administrative databases.
骨关节炎(OA)是一种高度常见且往往导致残疾的疾病。关于普通人群中OA发病率的数据有限。我们的目标是:(1)利用一个行政数据库,估算在一个地理区域限定的400万人口(加拿大不列颠哥伦比亚省)中按年龄和性别划分的OA患病率和发病率;(2)确定OA的不同行政定义以及观察(导入)时间对此类估算的影响。
我们使用了1991 - 1992财年至2000 - 2001财年不列颠哥伦比亚省医疗服务计划(MSP)涵盖的所有就医和住院数据。OA是根据《国际疾病分类》第9版用于行政目的所需的诊断编码来定义的。
2001年OA的总体患病率为10.8%:男性为8.9%,女性为12.6%。在所有年龄组中女性患病率更高。到70 - 74岁时,约三分之一的男性和40%的女性患有OA。2000 - 2001年的发病率在总人口中为每1000人年11.7例,男性为10.0例,女性为13.4例。在50至80岁之间发病率随年龄呈线性增加。患病率和发病率都强烈依赖于OA的定义和导入期。
不列颠哥伦比亚省医生诊断的OA患病率略低于人口调查中自我报告的关节炎患病率。常规收集的行政数据可能是OA监测的宝贵信息来源,但需要对行政数据库中OA诊断的有效性进行更多研究。