Sun Y, Stürmer T, Günther K P, Brenner H
Abteilung Epidemiologie, Universität Ulm.
Z Orthop Ihre Grenzgeb. 1997 May-Jun;135(3):184-92. doi: 10.1055/s-2008-1039578.
Analysis of data on the incidence and prevalence of osteoarthritis (OA) of the hip and knee in the general population.
Review of relevant investigations concerning epidemiology of hip and knee OA.
Estimates of incidence and prevalence of OA of the hip and knee vary considerably among 29 studies from 14 countries and 4 ethnic groups (incidence: 10 to 2230 per 10(5) person-years, prevalence: 0.5% to 36%.
Because of the differences in study design, study populations, and the definition of OA, a comparison between different studies is very difficult. Nevertheless, the following patterns can be identified: In general, both the incidence and prevalence of OA of the hip and knee increase with age. The sharp increase in incidence of symptomatic OA of the knee after age 50 in women suggests an influence of menopausal changes of hormonal status. The prevalence of radiographically defined OA of the hip is higher in men than in women, but a reverse pattern was found for OA of the knee, especially after age 45. The prevalence of radiographically OA was found to be higher in caucasian than non-caucasian populations at the hip but not the knee joint. Among patients with radiographically defined OA at the hip, joint pain seems to be more common in women than in men. In contrast, the frequency of joint pain in persons with radiographically defined OA of the knee is about the same in women and men.
分析普通人群中髋部和膝部骨关节炎（OA）的发病率和患病率数据。
回顾有关髋部和膝部OA流行病学的相关调查。
来自14个国家和4个种族的29项研究中，髋部和膝部OA发病率和患病率的估计值差异很大（发病率：每10（5）人年10至2230例，患病率：0.5%至36%）。
由于研究设计、研究人群和OA定义的差异，不同研究之间的比较非常困难。然而，可以确定以下模式：一般来说，髋部和膝部OA的发病率和患病率均随年龄增长而增加。50岁后女性膝部症状性OA发病率急剧上升，提示激素状态的绝经变化有影响。X线片定义的髋部OA患病率男性高于女性，但膝部OA发现相反模式，尤其是45岁以后。在髋部，X线片定义的OA患病率白种人高于非白种人群，但膝关节并非如此。在X线片定义的髋部OA患者中，关节疼痛在女性中似乎比男性更常见。相比之下，X线片定义的膝部OA患者中关节疼痛的频率在女性和男性中大致相同。
