Smith M V, Apkarian A V
Neurosurgery Research Laboratories, SUNY Health Science Center, Syracuse 13210.
Brain Res. 1991 Jul 26;555(1):10-8. doi: 10.1016/0006-8993(91)90853-n.
The number, location, and morphology of thalamically projecting lateral cervical nucleus (LCN) cells were determined in monkey using retrograde transport of wheatgerm agglutinin-conjugated horseradish peroxidase. These data were compared to the total population of LCN neurons as determined by Nissl stain. In 4 Macaca fascicularis and one Saimiri sciureus the average size of the thalamic projection from LCN was found to be 506 +/- 94 cells contralateral to the injections. Thalamically projecting LCN neurons were located between the lower medulla and the third cervical segment; approximately 90% of these cells were in the first two cervical segments. Morphologic analysis of thalamically projecting LCN cells showed that they were smaller in size, and more oblong in shape in caudal regions of the nucleus. In 3 macaques, the average total number of LCN cells was determined to be 1617 +/- 908 on one side, in Nissl material. In these Nissl-stained preparations LCN neurons were found as far caudal as the fourth cervical segment; 68% were located in the first two cervical segments. Hence, thalamically projecting LCN neurons in the monkey are located in the rostral portion of the nucleus and comprise about one-third of the total population. Comparison of these data with reports in the literature imply that, unlike the cat, the major projection from LCN in monkeys is to the mesencephalon rather than to the thalamus.
利用结合了辣根过氧化物酶的麦胚凝集素逆行运输法，在猴子身上确定了丘脑投射性外侧颈核（LCN）细胞的数量、位置和形态。将这些数据与通过尼氏染色确定的LCN神经元总数进行了比较。在4只食蟹猴和1只松鼠猴中，发现LCN向丘脑的投射平均大小为注射对侧506±94个细胞。丘脑投射性LCN神经元位于延髓下部和第三颈段之间；其中约90%的细胞位于前两个颈段。对丘脑投射性LCN细胞的形态学分析表明，它们在核的尾侧区域体积较小，形状更呈椭圆形。在3只猕猴中，通过尼氏染色材料确定一侧LCN细胞的平均总数为1617±908个。在这些尼氏染色制剂中，LCN神经元在第四颈段的尾侧也有发现；68%位于前两个颈段。因此，猴子的丘脑投射性LCN神经元位于核的头侧部分，约占总数的三分之一。将这些数据与文献报道进行比较表明，与猫不同，猴子LCN的主要投射是到中脑而不是丘脑。
