Beyrouti Mohamed Issam, Beyrouti Ramez, Khabir Abdelmajid, Ben Amar Mohamed, Frikha Foued, Dhieb Nabil, Damak Dalel, Abid Mohamed, Affes Najmeddine, Boujelben Salah, Frikha Mounir
Service de Chirurgie Génrale, EPS Habib Bomurgiiba, Sfax, Tunisie.
Tunis Med. 2006 Oct;84(10):626-31.
Our aim was to identify the predictive factors of degeneration of the fibrocystic mastopathy.
This work is a retrospective survey of 111 observations of isolated fibrocystic mastopathies or associated to a breast cancer among 542 women admitted for tumor of the breast during one period of 13 active years from 1991 to 2003. The diagnosis has been gotten by anatomo-pathologic exam in 95.5% (106 cas) on the operative piece and 4.5% (5 cas) on a material of biopsy.
The fibrocystic mastopathy represented 30% of the set of the benign tumors of the breast. They were associated to a breast cancer in 45 cases (40.5%). The isolated benign fibrocystic mastopathy was observed in 66 cases with a middle age of 37 years, whereas the shapes associated to a breast carcinoma were noted in 45 cases. The middle age was 53 years. The non proliferative fibrocystic mastopathy is the most frequent histological type and represent 54.6% of the cases. The proliferative form with atypies was observed at 21 women (46.8%). The carcinoma the more frequently associated to the fibrocystic mastopathy was the infiltrating canalled carcinoma in 91% of cases, with a predominance of the II rank (SBR).
The discovery of a mastopathy must search a luteal failure and risk factors of breast cancer notably a proliferative shape of mastopathy with atypies.
我们的目的是确定纤维囊性乳腺病退变的预测因素。
这项工作是对1991年至2003年13个活跃年份期间因乳腺肿瘤入院的542名女性中111例孤立性纤维囊性乳腺病或与乳腺癌相关病例的回顾性调查。95.5%（106例）通过手术标本的解剖病理检查确诊，4.5%（5例）通过活检材料确诊。
纤维囊性乳腺病占乳腺良性肿瘤总数的30%。它们与45例（40.5%）乳腺癌相关。观察到66例孤立性良性纤维囊性乳腺病，平均年龄37岁，而45例观察到与乳腺癌相关的类型，平均年龄53岁。非增生性纤维囊性乳腺病是最常见的组织学类型，占病例的54.6%。21名女性（46.8%）观察到有非典型增生的增生性类型。与纤维囊性乳腺病最常相关的癌是浸润性导管癌，占91%的病例，以II级（SBR）为主。
发现乳腺病必须寻找黄体功能不全和乳腺癌的危险因素，尤其是有非典型增生的增生性乳腺病类型。
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