Kain Zeev N, Caldwell-Andrews Alison A, Mayes Linda C, Weinberg Megan E, Wang Shu-Ming, MacLaren Jill E, Blount Ronald L
Center for the Advancement of Perioperative Health and the Department of Anesthesiology, Yale University School of Medicine, New Haven, Connecticut 06510, USA.
Anesthesiology. 2007 Jan;106(1):65-74. doi: 10.1097/00000542-200701000-00013.
Children and parents experience significant anxiety and distress during the preoperative period. Currently available interventions are having limited efficacy. Based on an integration of the literature in both the anesthesia and psychological milieus, the authors developed a behaviorally oriented perioperative preparation program for children undergoing surgery that targets the family as a whole.
Children and their parents (n = 408) were randomly assigned to one of four groups: (1) control: received standard of care; (2) parental presence: received standard parental presence during induction of anesthesia; (3) ADVANCE: received family-centered behavioral preparation; and (4) oral midazolam. The authors assessed the effect of group assignment on preoperative anxiety levels and postoperative outcomes such as analgesic consumption and emergence delirium.
Parents and children in the ADVANCE group exhibited significantly lower anxiety in the holding area as compared with all three other groups (34.4+/-16 vs. 39.7+/-15; P=0.007) and were less anxious during induction of anesthesia as compared with the control and parental presence groups (44.9+/-22 vs. 51.6+/-25 and 53.6+/-25, respectively; P=0.006). Anxiety and compliance during induction of anesthesia was similar for children in both the ADVANCE and midazolam groups (44.9+/-22 vs. 42.9+/-24; P=0.904). Children in the ADVANCE group exhibited a lower incidence of emergence delirium after surgery (P=0.038), required significantly less analgesia in the recovery room (P=0.016), and were discharged from the recovery room earlier (P=0.04) as compared with children in the three other groups.
The family-centered preoperative ADVANCE preparation program is effective in the reduction of preoperative anxiety and improvement in postoperative outcomes.
儿童及其家长在术前阶段会经历显著的焦虑和痛苦。目前可用的干预措施效果有限。基于麻醉学和心理学领域文献的综合分析,作者为接受手术的儿童制定了一项以行为为导向的围手术期准备计划,该计划以整个家庭为目标。
将儿童及其家长(n = 408)随机分为四组之一:(1)对照组:接受标准护理;(2)家长陪伴组:在麻醉诱导期间接受标准的家长陪伴;(3)ADVANCE组:接受以家庭为中心的行为准备;(4)口服咪达唑仑组。作者评估了分组对术前焦虑水平和术后结果(如镇痛药物用量和苏醒期谵妄)的影响。
与其他三组相比,ADVANCE组的家长和儿童在等待区表现出显著更低的焦虑(34.4±16 vs. 39.7±15;P = 0.007),并且与对照组和家长陪伴组相比,在麻醉诱导期间焦虑程度更低(分别为44.9±22 vs. 51.6±25和53.6±25;P = 0.006)。ADVANCE组和咪达唑仑组儿童在麻醉诱导期间的焦虑和依从性相似(44.9±22 vs. 42.9±24;P = 0.904)。与其他三组儿童相比,ADVANCE组儿童术后苏醒期谵妄的发生率更低(P = 0.038),在恢复室所需的镇痛药物显著更少(P = 0.016),并且更早从恢复室出院(P = 0.04)。
以家庭为中心的术前ADVANCE准备计划在降低术前焦虑和改善术后结果方面是有效的。