Wu Zhong, Ding Qiang, Jiang Hao-wen, Chen Zhi-xin, Zhang Hua-wei, Li Chun-jun, Zhang Yuan-fan
Department of Urology, Huashan Hospital, Fudan University, Shanghai 200040, China.
Zhonghua Yi Xue Za Zhi. 2006 Sep 26;86(36):2560-2.
To evaluate the efficacy and safety of transurethral holmium laser enucleation of the prostate (HoLEP) for the treatment of benign prostatic hyperplasia (BPH).
A retrospective review was conducted of transurethral (HoLEP) performed on 68 patients, aged 65.7 (50 - 91) with benign prostatic hyperplasia. The efficacy and complications were all assessed.
The mean procedure time was 87 mins (45 - 158 mins). The mean specimen weight was 61 g (31 - 128 g). The procedure allows a precise, bloodless field with no need for transfusion. No TUR syndrome and other major complications were encountered during the operation. The mean catheter time and hospital stay were 2.8 d (1 - 4 d) and 3.6 d (2 - 5 d), respectively. Follow-up of 7.6 months (1 - 13 months) revealed that the urination symptoms were markedly improved in all patients, and that the IPSS decreased from 25.7 +/- 6.9 to 7.7 +/- 4.3 (P < 0.01) and the maximum urine flow rate increased from 8.1 +/- 4.2 ml/s to 18.8 +/- 4.6 ml/s (P < 0.01). Postoperative complications occurred in 3 patients. 2 with transient incontinence were recovered within 3 months postoperatively. The other one with mild posterior urethral stricture was treated effectively with urethral sounding.
Was associated with high effectiveness, safety, short hospital stay and less complications, HoLEP is a new minimally invasive surgical procedure for BPH.
评估经尿道钬激光前列腺剜除术(HoLEP)治疗良性前列腺增生(BPH)的疗效和安全性。
对68例年龄为65.7岁(50 - 91岁)的良性前列腺增生患者行HoLEP手术进行回顾性分析。评估手术疗效及并发症。
平均手术时间为87分钟(45 - 158分钟)。平均标本重量为61克(31 - 128克)。该手术可提供精确的无血视野,无需输血。术中未发生经尿道电切综合征及其他严重并发症。平均导尿管留置时间和住院时间分别为2.8天(1 - 4天)和3.6天(2 - 5天)。7.6个月(1 - 13个月)的随访结果显示,所有患者排尿症状均明显改善,国际前列腺症状评分(IPSS)从25.7±6.9降至7.7±4.3(P < 0.01),最大尿流率从8.1±4.2毫升/秒增至18.8±4.6毫升/秒(P < 0.01)。3例患者出现术后并发症。2例短暂性尿失禁患者在术后3个月内恢复。另1例轻度后尿道狭窄患者经尿道探条扩张治疗有效。
HoLEP疗效高、安全性好、住院时间短且并发症少,是一种治疗BPH的新型微创手术方法。