Dudin A A, Rambaud-Cousson A, Thalji A, Juabeh I I, Abu-Libdeh B
Department of Paediatrics, Makassed Islamic Charitable Hospital, Jerusalem, Israel.
Ann Trop Paediatr. 1991;11(3):217-23. doi: 10.1080/02724936.1991.11747506.
Fifty-four children from the Jerusalem area were studied prospectively following scorpion envenoming. Their ages ranged from 11 months to 10 years. Severe symptoms (convulsions, brain oedema, shock, respiratory distress and myocarditis) were encountered in 19. Respiratory distress was the main feature in 17 of the children, in two cases owing to pulmonary oedema and in a third because of adult respiratory distress syndrome and myocarditis; mechanical ventilation was required in three cases. The severity of the symptoms and signs was not related to sex, age, weight, interval between scorpion sting and admission or to the type of offending scorpion; it was most likely dependent upon the susceptibility of the individual and/or the dose of venom injected by the scorpion. Intravenous antivenom quickly reversed the symptoms, and no side-effects were seen in the patients studied. The two patients who died had not received the antivenom intravenously. We recommend that specific antivenom should be given intravenously in all children who show significant symptoms. Furthermore, a longer period of observation is necessary following scorpion sting in this age group.
对耶路撒冷地区的54名儿童在被蝎子蜇伤后进行了前瞻性研究。他们的年龄从11个月到10岁不等。19名儿童出现了严重症状(惊厥、脑水肿、休克、呼吸窘迫和心肌炎)。17名儿童的主要特征是呼吸窘迫,其中2例是由于肺水肿,第3例是由于成人呼吸窘迫综合征和心肌炎;3例需要机械通气。症状和体征的严重程度与性别、年龄、体重、蝎子蜇伤与入院之间的间隔时间或致伤蝎子的种类无关;最有可能取决于个体的易感性和/或蝎子注入的毒液剂量。静脉注射抗蛇毒血清可迅速缓解症状,在所研究的患者中未观察到副作用。死亡的两名患者未接受静脉注射抗蛇毒血清。我们建议,所有出现明显症状的儿童都应静脉注射特异性抗蛇毒血清。此外,这个年龄组的儿童在被蝎子蜇伤后需要更长时间的观察。