Bawaskar H S, Bawaskar P H
Bawaskar Hospital and Research Centre, Mahad Raigad, Maharashtra.
Indian J Pediatr. 1998 May-Jun;65(3):383-91. doi: 10.1007/BF02761131.
The clinical course and treatment outcome of scorpion envenoming in 293 children was studied in a hospital at Mahad in Raigad district of Maharastra. 111 (38%) children who reported 1-10 hours (mean 3.5 hours) after sting had hypertension, 87 (29.6%) with tachycardia reported within 1-24 hours (mean 6.7 hours) of being envenomed and 72 (24.5%) children developed acute pulmonary edema after 6-24 hours (mean 8 hours) of sting. Six victims were brought dead, while 17 (6%) died later owing to multiorgan failure with loss of consciousness and convulsions (who reported after 24 hours of sting). Early administration of prazosin (125-250 ug orally) improved the clinical symptoms. Morbidity and mortality due to scorpion envenoming depends upon time lapse between sting and administration of post synaptic alpha-1 blocker, prazosin hydrochloride.
在马哈拉施特拉邦赖加德区马哈德的一家医院,对293名儿童蝎子蜇伤的临床病程和治疗结果进行了研究。111名(38%)在蜇伤后1 - 10小时(平均3.5小时)前来就诊的儿童出现高血压,87名(29.6%)在被蜇伤后1 - 24小时(平均6.7小时)内出现心动过速,72名(24.5%)儿童在蜇伤后6 - 24小时(平均8小时)出现急性肺水肿。6名受害者送来时已死亡,另有17名(6%)后来因多器官功能衰竭伴意识丧失和抽搐(在蜇伤24小时后前来就诊)而死亡。早期给予哌唑嗪(口服125 - 250微克)可改善临床症状。蝎子蜇伤导致的发病率和死亡率取决于蜇伤与给予突触后α-1阻滞剂盐酸哌唑嗪之间的时间间隔。