Hopper Kate, Haskins Steve C, Kass Philip H, Rezende Marlis L, Aldrich Janet
Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
J Am Vet Med Assoc. 2007 Jan 1;230(1):64-75. doi: 10.2460/javma.230.1.64.
To determine outcome of positive-pressure ventilation (PPV) for 24 hours or longer and identify factors associated with successful weaning from PPV and survival to hospital discharge in dogs and cats.
Retrospective case series.
124 dogs and 24 cats that received PPV for 24 hours or longer.
Medical records were reviewed for signalment, primary diagnosis, reason for initiating PPV, measures of oxygenation and ventilation before and during PPV, ventilator settings, complications, duration of PPV, and outcome. Animals were categorized into 1 of 3 groups on the basis of the reason for PPV.
Group 1 patients received PPV for inadequate oxygenation (67 dogs and 6 cats), group 2 for inadequate ventilation (46 dogs and 16 cats), and group 3 for inadequate oxygenation and ventilation (11 dogs and 2 cats). Of the group 1 animals, 36% (26/73) were weaned from PPV and 22% (16/73) survived to hospital discharge. In group 2, 50% (31/62) were weaned from PPV and 39% (24/62) survived to hospital discharge. In group 3, 3 of 13 were weaned from PPV and 1 of 13 survived to hospital discharge. Likelihood of successful weaning and survival to hospital discharge were significantly higher for group 2 animals, and cats had a significantly lower likelihood of successful weaning from PPV, compared with dogs. Median duration of PPV was 48 hours (range, 24 to 356 hours) and was not associated with outcome.
Results suggested that long-term PPV is practical and successful in dogs and cats.
确定持续24小时或更长时间的正压通气(PPV)的结果,并识别与犬猫成功撤机及存活至出院相关的因素。
回顾性病例系列研究。
124只犬和24只猫接受了24小时或更长时间的PPV。
查阅病历以获取动物的特征、初步诊断、开始PPV的原因、PPV前及期间的氧合和通气指标、呼吸机设置、并发症、PPV持续时间及结果。根据PPV的原因将动物分为3组。
第1组患者因氧合不足接受PPV(67只犬和6只猫),第2组因通气不足接受PPV(46只犬和16只猫),第3组因氧合和通气不足接受PPV(11只犬和2只猫)。第1组动物中,36%(26/73)成功撤机,22%(16/73)存活至出院。第2组中,50%(31/62)成功撤机,39%(24/62)存活至出院。第3组中,13只中有3只成功撤机,13只中有1只存活至出院。与第1组和第3组相比,第2组动物成功撤机及存活至出院的可能性显著更高,与犬相比,猫成功撤机的可能性显著更低。PPV的中位持续时间为48小时(范围为24至356小时),且与结果无关。
结果表明,长期PPV在犬猫中是可行且成功的。