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因椎间盘突出导致颈椎脊髓病而接受腹侧开槽减压手术的犬的亚临床通气不足

Subclinical Hypoventilation in Dogs Undergoing Ventral Slot Decompressive Surgery for Cervical Myelopathy Due to Intervertebral Disc Herniation.

作者信息

Andruzzi Melissa N, Simon Bradley T, Boudreau Elizabeth

机构信息

Department of Small Animal Clinical Sciences, Texas A&M University, College Station, TX, United States.

出版信息

Front Vet Sci. 2021 Nov 4;8:777052. doi: 10.3389/fvets.2021.777052. eCollection 2021.

DOI:10.3389/fvets.2021.777052
PMID:34805345
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8599362/
Abstract

The objective of this prospective cohort study was to document the occurrence of post-operative hypoventilation in dogs undergoing decompressive ventral slot or hemilaminectomy for the treatment of intervertebral disc herniation (IVDH). Twenty dogs undergoing ventral slot surgery and 20 dogs undergoing hemilaminectomy surgery for the treatment of IVDH that presented to XX between 2017 and 2020 were enrolled. Dogs were anesthetized using a standard protocol. Blood gas samples were taken at up to 11 time points beginning during anesthetic recovery and continuing for a maximum of 72 h post-operatively. Dogs with cervical lesions that were non-ambulatory before surgery had more evidence of subclinical hypoventilation in the immediate peri-extubation period than dogs with less severe injuries or those undergoing hemilaminectomy surgery. We found no difference in the ventilation status in dogs undergoing cervical or thoracolumbar decompressive surgery for IVDH from 8 to 72 h post-operatively. Other markers of acid-base status indicated that subclinical hypoventilation within the peri-extubation period was transient and self-limiting. There was a moderate positive correlation between sedation scores and estimated PaCO. These data suggest that dogs with severe cervical spinal cord injuries may be at risk for subclinical hypoventilation in the immediate peri-extubation period. Increased sedation may be correlated with decreased ventilatory status in dogs recovering from decompressive vertebral column surgery.

摘要

这项前瞻性队列研究的目的是记录因治疗椎间盘突出症(IVDH)而接受减压性腹侧开槽术或半椎板切除术的犬只术后通气不足的发生情况。纳入了2017年至2020年间到XX就诊、因治疗IVDH而接受腹侧开槽手术的20只犬和接受半椎板切除手术的20只犬。犬只采用标准方案进行麻醉。在麻醉苏醒期间开始,最多在11个时间点采集血气样本,并在术后最多持续72小时。术前不能行走的颈椎病变犬在拔管即刻比损伤较轻的犬或接受半椎板切除手术的犬有更多亚临床通气不足的证据。我们发现,因IVDH接受颈椎或胸腰椎减压手术的犬在术后8至72小时通气状态无差异。酸碱状态的其他指标表明,拔管期间的亚临床通气不足是短暂且自限性的。镇静评分与估计的动脉血二氧化碳分压(PaCO)之间存在中度正相关。这些数据表明,严重颈椎脊髓损伤的犬在拔管即刻可能存在亚临床通气不足的风险。在从减压性脊柱手术恢复的犬中,镇静程度增加可能与通气状态下降相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df5/8599362/2404aa68e67d/fvets-08-777052-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df5/8599362/f89b13fafc3a/fvets-08-777052-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df5/8599362/f1a0f273b49e/fvets-08-777052-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df5/8599362/b0cc2842abf5/fvets-08-777052-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df5/8599362/746c666451cd/fvets-08-777052-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df5/8599362/e53bba314e54/fvets-08-777052-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df5/8599362/2404aa68e67d/fvets-08-777052-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df5/8599362/f89b13fafc3a/fvets-08-777052-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df5/8599362/f1a0f273b49e/fvets-08-777052-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df5/8599362/b0cc2842abf5/fvets-08-777052-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df5/8599362/746c666451cd/fvets-08-777052-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df5/8599362/e53bba314e54/fvets-08-777052-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9df5/8599362/2404aa68e67d/fvets-08-777052-g0006.jpg

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