炭疽芽孢杆菌疫苗株“Carbosap”中参与毒力调控途径的基因的分子研究
Molecular study of genes involved in virulence regulatory pathways in Bacillus anthracis vaccine strain "Carbosap".
作者信息
La Rosa Giuseppina, Muscillo Michele, Sali Michela, De Carolis Elena, Marianelli Cinzia, Ciuchini Franco, Fasanella Antonio, Adone Rosanna
机构信息
Istituto Superiore di Sanità, Environmental and Primary Prevention Department, Viale Regina Elena 299, 00161, Rome, Italy.
出版信息
New Microbiol. 2006 Oct;29(4):307-10.
PMID:17201098
Abstract
This study investigated the genetic bases of attenuation in the Bacillus anthracis vaccine strain "Carbosap" used in Italy against anthrax in cattle and sheep. Twelve genes involved in virulence regulatory pathways underwent sequence analysis in comparison with a B. anthracis virulent strain.
摘要
本研究调查了意大利用于预防牛羊炭疽的炭疽芽孢杆菌疫苗株“Carbosap”减毒的遗传基础。与一株炭疽芽孢杆菌强毒株相比，对参与毒力调控途径的12个基因进行了序列分析。
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