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大Y染色体对体外受精和胚胎移植结局无显著影响

[Big Y chromosome not significantly influences outcomes of in vitro fertilization and embryo transfer].

作者信息

Hu Xiao-dong, Zeng Yong, Mo Mei-lan, Lin Qi, Cai Jing, Guo Chu-ping, Deng Jiang-lin

机构信息

ART Center, Shenzhen Zhongshan Urology Hospital, Shenzhen, Guangdong 518000, China.

出版信息

Zhonghua Nan Ke Xue. 2006 Dec;12(12):1088-90.

PMID:17201253
Abstract

OBJECTIVE

To evaluate the influence of big Y chromosome on the outcomes of in vitro fertilization and embryo transfer.

METHODS

Data of 127 cycles of IVF/ICSI-ET, performed in our Reproductive Medicine Center from March 2001 to June 2003 were analyzed. The patients were divided into two groups according to the length of chromosome: Group A, 56 cycles with big Y chromosome

RESULTS

No significant difference was observed in the quality of embryos and in the and Group B, 71 cycles with normal karyotype. rates of fertilization, cleavage, clinical pregnancy, implantation, miscarriage, ectopic pregnancy, dead infant delivery, malformation,

CONCLUSION

Big Y chromosome has no significant influence on the baby boy delivery and baby girl delivery between the two groups. development of embryos and the outcome of pregnancy.

摘要

目的

评估大Y染色体对体外受精和胚胎移植结局的影响。

方法

分析2001年3月至2003年6月在本生殖医学中心进行的127个体外受精/卵胞浆内单精子注射-胚胎移植周期的数据。根据染色体长度将患者分为两组:A组,56个周期有大Y染色体;B组,71个周期核型正常。

结果

两组在胚胎质量、受精率、卵裂率、临床妊娠率、着床率、流产率、异位妊娠率、死产率、畸形率、男婴出生率和女婴出生率方面均未观察到显著差异。

结论

大Y染色体对胚胎发育及妊娠结局无显著影响。

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引用本文的文献

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Y chromosome polymorphisms contribute to an increased risk of non-obstructive azoospermia: a retrospective study of 32,055 Chinese men.Y 染色体多态性增加非梗阻性无精子症风险:32055 例中国男性的回顾性研究。
J Assist Reprod Genet. 2024 Mar;41(3):757-765. doi: 10.1007/s10815-024-03022-y. Epub 2024 Jan 25.
2
Long Y chromosome is not a fetal loss risk.长 Y 染色体不是胎儿丢失的风险因素。
J Assist Reprod Genet. 2011 Feb;28(2):151-6. doi: 10.1007/s10815-010-9497-1. Epub 2010 Nov 17.