Roman Christopher, Nebieridze Nino, Sastre Aristides, Reilly Steve
Department of Psychology, University of Illinois at Chicago, Chicago, IL 60607, USA.
Behav Neurosci. 2006 Dec;120(6):1257-67. doi: 10.1037/0735-7044.120.6.1257.
The effects of permanent forebrain lesions on conditioned taste aversions (CTAs) and conditioned odor aversions (COAs) were examined in 3 experiments. In Experiment 1, lesions of the bed nucleus of the stria terminalis had no influence on CTA or COA acquisition. Although lesions of the lateral hypothalamus induced severe hypodipsia in Experiment 2, they did not prevent the acquisition of CTAs or COAs. Finally, in Experiment 3, lesions of the insular cortex retarded CTA acquisition but had no influence on COA acquisition. The implications of these findings are discussed with regard to the forebrain influence on parabrachial nucleus function during CTA acquisition.
在3项实验中研究了永久性前脑损伤对条件性味觉厌恶（CTA）和条件性气味厌恶（COA）的影响。在实验1中，终纹床核损伤对CTA或COA的习得没有影响。虽然在实验2中下丘脑外侧损伤导致严重的饮水过少，但并未阻止CTA或COA的习得。最后，在实验3中，岛叶皮质损伤延缓了CTA的习得，但对COA的习得没有影响。结合前脑在CTA习得过程中对臂旁核功能的影响对这些发现的意义进行了讨论。
