Chinushi Masaomi, Izumi Daisuke, Furushima Hiroshi, Watanabe Hiroshi, Aizawa Yoshifusa
School of Health Science, Niigata University School of Medicine, Niigata, Japan.
Pacing Clin Electrophysiol. 2006 Dec;29(12):1445-8. doi: 10.1111/j.1540-8159.2006.00562.x.
A 17-year-old man was referred to our hospital for treatment of common paroxysmal atrial flutter. His electrocardiogram at rest showed subtle ST-segment elevation in leads II, III, and aV(F). Intravenous pilsicainide caused further ST-segment elevation in the inferior leads, new ST-segment depression in leads V2-V6, two distinct forms of premature ventricular complexes (PVCs) triggering short runs of polymorphic ventricular tachycardia (VT). An infusion of isoproterenol suppressed these arrhythmias and normalized the ST-segment. Pilsicainide may induce PVCs and polymorphic VT in atypical Brugada syndrome.
一名17岁男性因普通阵发性心房扑动被转诊至我院治疗。他静息时的心电图显示II、III和aV(F)导联有轻微ST段抬高。静脉注射吡西卡尼导致下壁导联ST段进一步抬高，V2-V6导联出现新的ST段压低，两种不同形式的室性早搏（PVC）引发了短阵多形性室性心动过速（VT）。静脉滴注异丙肾上腺素抑制了这些心律失常并使ST段恢复正常。吡西卡尼可能会在非典型Brugada综合征中诱发PVC和多形性VT。
