对啮齿动物致癌性一些短期试验预测性的量化。
Quantification of the predictivity of some short-term assays for carcinogenicity in rodents.
作者信息
Klopman G, Rosenkranz H S
机构信息
Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106.
出版信息
Mutat Res. 1991 Dec;253(3):237-40. doi: 10.1016/0165-1161(91)90136-v.
PMID:1720198
Abstract
A statistical procedure is described for assessing the predictive performance of short-term tests for carcinogenicity in which the actual number of chemicals tested is taken into consideration. The method is then applied to several widely used short-term assays.
摘要
描述了一种统计程序，用于评估致癌性短期试验的预测性能，其中考虑了实际测试的化学物质数量。然后将该方法应用于几种广泛使用的短期试验。
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