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甲硝唑治疗后细菌性阴道病菌群变化的非培养分析

Cultivation-independent analysis of changes in bacterial vaginosis flora following metronidazole treatment.

作者信息

Ferris Michael J, Norori Johana, Zozaya-Hinchliffe Marcela, Martin David H

机构信息

Department of Pediatrics, Louisiana State University Health Sciences Center, New, Orleans, Louisiana 70112, USA.

出版信息

J Clin Microbiol. 2007 Mar;45(3):1016-8. doi: 10.1128/JCM.02085-06. Epub 2007 Jan 3.

Abstract

PCR was used to survey bacterial vaginosis flora before and after metronidazole treatment. The species composition for pretreatment patients was variable. Lactobacillus iners was prominent in all patients posttreatment. Atopobium vaginae concentrations were highest for patients who failed or responded incompletely to treatment and lowest for patients who were cured.

摘要

采用聚合酶链反应(PCR)检测甲硝唑治疗前后细菌性阴道病的菌群。治疗前患者的菌种组成各不相同。惰性乳杆菌在所有治疗后的患者中占主导地位。阴道阿托波菌浓度在治疗失败或反应不完全的患者中最高,而在治愈的患者中最低。

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