IAPP mimic blocks Abeta cytotoxic self-assembly: cross-suppression of amyloid toxicity of Abeta and IAPP suggests a molecular link between Alzheimer's disease and type II diabetes.
作者信息
Yan Li-Mei, Velkova Aleksandra, Tatarek-Nossol Marianna, Andreetto Erika, Kapurniotu Aphrodite
机构信息
Laboratory of Bioorganic and Medicinal Chemistry, Institute of Biochemistry, University Hospital of the RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany.
出版信息
Angew Chem Int Ed Engl. 2007;46(8):1246-52. doi: 10.1002/anie.200604056.
PMID:17203498
Abstract
摘要
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