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[自发性食管穿孔的治疗与病程]

[Therapy and course of disease in spontaneous esophageal perforations].

作者信息

Thermann F, Thermann M, Dralle H

机构信息

Klinik für Allgemein-, Viszeral- und Gefässchirurgie, Medizinische Fakultät Universität Halle, Universitätsklinikum Halle-Kröllwitz.

出版信息

Zentralbl Chir. 2006 Dec;131(6):454-9. doi: 10.1055/s-2006-955447.

Abstract

INTRODUCTION

Esophageal perforations occur spontaneously or as a complication of endoscopic procedures. Especially in spontaneous perforation there is ongoing debate regarding the best treatment options.

METHODS

24 patients that were treated at two surgical centers (University Halle, City-hospital Bielefeld) after spontaneous esophageal perforations between 1996 and 2005 were analysed retrospectively.

RESULTS

All patients but one underwent surgical treatment with in 2 cases additional stent implantation. Average stay in hospital was 53 days. In-hospital-lethality was 25% (overall lethality 37.5%). Concerning the therapeutic outcome there was no link between patients' age, localization or size of the perforation and the time interval between perforation and treatment. In 22 patients diagnosis was made > 12hrs after the event.

CONCLUSIONS

Main problem of the Boerhaave-syndrome is the septic-toxic disease. Prognostic criteria are the patients' health-state and not factors like size of perforation, time of delay or localization of the perforation. Since in case of survival esophageal resection shows good long-term-results, in doubt a radical surgical procedure should be recommended as primary option. Implanting an esophageal stent might become a useful mean of treating patients with spontaneous perforations.

摘要

引言

食管穿孔可自发发生,也可作为内镜手术的并发症出现。尤其是在自发性穿孔方面,关于最佳治疗方案一直存在争议。

方法

回顾性分析了1996年至2005年间在两个外科中心(哈雷大学、比勒费尔德市立医院)接受自发性食管穿孔治疗的24例患者。

结果

除1例患者外,所有患者均接受了手术治疗,其中2例额外植入了支架。平均住院时间为53天。院内死亡率为25%(总死亡率为37.5%)。关于治疗结果,患者的年龄、穿孔部位或大小以及穿孔与治疗之间的时间间隔之间没有关联。22例患者在事件发生后> 12小时才确诊。

结论

博赫哈夫综合征的主要问题是感染性中毒疾病。预后标准是患者的健康状况,而非穿孔大小、延误时间或穿孔部位等因素。由于在存活的情况下食管切除术显示出良好的长期效果,如有疑问,应建议首选根治性手术。植入食管支架可能成为治疗自发性穿孔患者的一种有用手段。

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