组蛋白H1调节利什曼原虫中的染色质凝聚。
Histone H1 regulates chromatin condensation in Leishmania parasites.
作者信息
Masina Slavica, Zangger Haroun, Rivier Denis, Fasel Nicolas
机构信息
Department of Biochemistry, University of Lausanne, Chemin des Boveresses 155, CH-1066, Epalinges, Switzerland.
出版信息
Exp Parasitol. 2007 May;116(1):83-7. doi: 10.1016/j.exppara.2006.11.002. Epub 2007 Jan 4.
Abstract
We investigated the functional role of the Leishmania histone H1 and demonstrate for the first time that addition of histone H1 has a strong effect on microccocal digestion, chromatin condensation of parasite nuclei and that its overexpression can modulate parasite infectivity in vivo.
摘要
我们研究了利什曼原虫组蛋白H1的功能作用，并首次证明添加组蛋白H1对微球菌消化、寄生虫细胞核的染色质凝聚有强烈影响，且其过表达可在体内调节寄生虫的感染性。
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