Suppr超能文献

膝关节骨关节炎女性患者的半月板退变撕裂与活动能力受损

Degenerative meniscus tears and mobility impairment in women with knee osteoarthritis.

作者信息

Lange A K, Fiatarone Singh M A, Smith R M, Foroughi N, Baker M K, Shnier R, Vanwanseele B

机构信息

School of Exercise and Sport Science, Faculty of Health Sciences, University of Sydney, Sydney, Australia.

出版信息

Osteoarthritis Cartilage. 2007 Jun;15(6):701-8. doi: 10.1016/j.joca.2006.11.004. Epub 2007 Jan 3.

Abstract

OBJECTIVE

Meniscus tears are often presumed to be associated with a traumatic event, but they can also occur as a result of the cartilage degeneration process in osteoarthritis (OA). The aim of this paper is to describe the prevalence and clinical correlates of degenerative meniscus tears in women with knee OA.

METHOD

The subjects were women screened for a double-blind, sham-exercise controlled clinical trial for women over 40 years of age with OA in at least one knee, according to American College of Rheumatology (ACR) clinical criteria. The presence of meniscus tears was assessed via a 3T Intera (Philips Medical Systems) magnetic resonance image (MRI). Clinical examination included a history of arthritis onset and physical examination of the lower extremities. Physical assessments included body composition, muscle strength, walking endurance, gait velocity, and balance. In addition, pain and disability secondary to OA, physical self-efficacy, depressive symptoms, habitual physical activity level and quality of life were assessed via questionnaires.

RESULTS

Almost three-quarters (73%) of the 41 subjects had a medial, lateral, or bilateral meniscus tear by MRI. Walking endurance and balance performance were significantly impaired in subjects with a degenerative meniscus tear, compared to subjects without tears, despite similar OA duration, symptoms, and disability, body composition, and other clinical characteristics.

CONCLUSION

Meniscus tears, diagnosed by MRI, are very common in older women with knee OA, particularly in the medial compartment. These incidentally discovered tears are associated with clinically relevant impairments of balance and walking endurance relative to subjects without meniscus tears. The explanation for this association requires further study.

摘要

目的

半月板撕裂通常被认为与创伤事件有关,但也可能是骨关节炎(OA)中软骨退变过程的结果。本文旨在描述膝关节OA女性患者中退行性半月板撕裂的患病率及其临床相关因素。

方法

研究对象为根据美国风湿病学会(ACR)临床标准筛选出的年龄在40岁以上、至少一侧膝关节患有OA的女性,她们参与了一项双盲、假运动对照的临床试验。通过3T Intera(飞利浦医疗系统)磁共振成像(MRI)评估半月板撕裂的情况。临床检查包括关节炎发病史和下肢体格检查。身体评估包括身体成分、肌肉力量、步行耐力、步态速度和平衡能力。此外,通过问卷调查评估OA继发的疼痛和功能障碍、身体自我效能感、抑郁症状、习惯性身体活动水平和生活质量。

结果

41名受试者中,近四分之三(73%)通过MRI检查发现有内侧、外侧或双侧半月板撕裂。与没有半月板撕裂的受试者相比,尽管OA病程、症状、功能障碍、身体成分及其他临床特征相似,但患有退行性半月板撕裂的受试者的步行耐力和平衡能力明显受损。

结论

通过MRI诊断的半月板撕裂在老年膝关节OA女性中非常常见,尤其是在内侧间室。相对于没有半月板撕裂的受试者,这些偶然发现的撕裂与平衡和步行耐力的临床相关损害有关。这种关联的原因需要进一步研究。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验