Ardatov Oleg, Aleksiuk Viktorija, Maknickas Algirdas, Stonkus Rimantas, Uzieliene Ilona, Vaiciuleviciute Raminta, Pachaleva Jolita, Kvederas Giedrius, Bernotiene Eiva
Faculty of Mechanics, Vilnius Gediminas Technical University, LT-10223 Vilnius, Lithuania.
Department of Regenerative Medicine, State Research Institute Centre for Innovative Medicine, LT-08410 Vilnius, Lithuania.
Bioengineering (Basel). 2023 Mar 1;10(3):314. doi: 10.3390/bioengineering10030314.
The present study aims to explore the stressed state of cartilage using various meniscal tear models. To perform this research, the anatomical model of the knee joint was developed and the nonlinear mechanical properties of the cartilage and meniscus were verified. The stress-strain curve of the meniscus was obtained by testing fresh tissue specimens of the human meniscus using a compression machine. The results showed that the more deteriorated meniscus had greater stiffness, but its integrity had the greatest impact on the growth of cartilage stresses. To confirm this, cases of radial, longitudinal, and complex tears were examined. The methodology and results of the study can assist in medical diagnostics for meniscus treatment and replacement.
本研究旨在利用各种半月板撕裂模型探索软骨的应力状态。为开展此项研究,建立了膝关节的解剖模型,并验证了软骨和半月板的非线性力学特性。通过使用压力机测试人类半月板的新鲜组织标本,获得了半月板的应力-应变曲线。结果表明,退变越严重的半月板刚度越大,但其完整性对软骨应力的增长影响最大。为证实这一点,对放射状、纵向和复杂撕裂的病例进行了检查。该研究的方法和结果有助于半月板治疗和置换的医学诊断。