Melissano G, Civilini E, Bertoglio L, Calliari F, Setacci F, Calori G, Chiesa R
Department of Vascular Surgery, Vita - Salute University, Scientific Institute H. San Raffaele, Milan, Italy.
Eur J Vasc Endovasc Surg. 2007 May;33(5):561-6. doi: 10.1016/j.ejvs.2006.11.019. Epub 2007 Jan 3.
Endovascular approach to the aortic arch is an appealing solution for selected patients. Aim of this study is to compare the technical and clinical success recorded in the different anatomical settings of endografting for aortic arch disease.
Between June 1999 and October 2006, among 178 patients treated at our Institution for thoracic aorta disease with a stent-graft, the aortic arch was involved in 64 cases. According to the classification proposed by Ishimaru, aortic "zone 0" was involved in 14 cases, "zone 1" in 12 cases and "zone 2" in 38 cases. A hybrid surgical procedure of supraortic debranching and revascularization was performed in 37 cases to obtain an adequate proximal aortic landing zone.
"Zone 0" (14 cases). Proximal neck length: 44+/-6mm. Initial clinical success 78.6%: 2 deaths (stroke), 1 type Ia endoleak. At a mean follow-up of 16.4+/-11 months the midterm clinical success was 85.7%. "Zone 1" (12 cases). Proximal neck length: 28+/-5mm. Initial clinical success 66.7%: 0 deaths, 4 type Ia endoleaks. At a mean follow-up of 16.9+/-17.2 months the midterm clinical success was 75.0%. "Zone 2" (38 cases) Proximal neck length: 30+/-5mm. Initial clinical success 84.2%: 2 deaths (1 cardiac arrest, 1 multiorgan embolization), 3 type Ia endoleaks, 1 case of open conversion. Two cases of delayed transitory paraparesis/paraplegia were observed. At a mean follow-up of 28.0+/-17.2 months the midterm clinical success was 89.5%.
Total debranching of the arch for "zone 0" aneurysms allowed to obtain a longer proximal aortic landing zone with lower incidence of endoleak, however a higher risk of cerebrovascular accident was observed. The relatively high incidence of adverse events in "zone 1" could be associated to a shorter proximal neck, therefore this landing zone is reserved for patients unfit for sternotomy. In case of endoleak, discovered after a satisfactorily positioned endograft in the arch, the rate of spontaneous resolution within the first 6 months is high.
对于部分患者而言,经血管腔内途径治疗主动脉弓是一种颇具吸引力的解决方案。本研究旨在比较主动脉弓疾病腔内修复术在不同解剖情况下的技术成功率和临床成功率。
1999年6月至2006年10月期间,在我院接受胸主动脉疾病支架植入治疗的178例患者中,64例累及主动脉弓。根据石丸提出的分类方法,主动脉“0区”累及14例,“1区”累及12例,“2区”累及38例。37例患者采用主动脉弓上分支和血运重建的杂交手术,以获得足够的近端主动脉锚定区。
“0区”(14例)。近端颈部长度:44±6mm。初始临床成功率78.6%:2例死亡(中风),1例Ia型内漏。平均随访16.4±11个月时,中期临床成功率为85.7%。“1区”(12例)。近端颈部长度:28±5mm。初始临床成功率66.7%:无死亡,4例Ia型内漏。平均随访16.9±17.2个月时,中期临床成功率为75.0%。“2区”(38例)。近端颈部长度:30±5mm。初始临床成功率84.2%:2例死亡(1例心脏骤停,1例多器官栓塞),3例Ia型内漏,1例转为开放手术。观察到2例迟发性短暂性轻瘫/截瘫。平均随访28.0±17.2个月时,中期临床成功率为89.5%。
对于“0区”动脉瘤,完全去分支可获得更长的近端主动脉锚定区,内漏发生率较低,但脑血管意外风险较高。“1区”不良事件发生率相对较高可能与近端颈部较短有关,因此该锚定区仅适用于不宜行胸骨切开术的患者。如果在主动脉弓内移植物位置满意后发现内漏,在前6个月内自发闭合的几率较高。