Liu Yanxiang, Zhang Bowen, Liang Shenghua, Dun Yaojun, Guo Hongwei, Qian Xiangyang, Yu Cuntao, Sun Xiaogang
Department of Vascular Surgery, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Front Cardiovasc Med. 2022 Jun 2;9:882783. doi: 10.3389/fcvm.2022.882783. eCollection 2022.
The hybrid arch repair (HAR) is an appealing surgical option in the management of aortic arch diseases. The aim is to evaluate the short and mid-term outcomes of type II HAR involving replacement of the ascending aorta, arch debranching, and zone 0 stent graft deployment in diverse arch pathologies.
200 patients with various diffuse aortic pathologies involving the arch were enrolled between 2016 and 2019. Complex arch diseases included acute type A dissection ( = 129, 64.5%), acute type B dissection ( = 16, 8.0%), aortic arch aneurysm ( = 42, 21.0%) and penetrating arch ulcer ( = 13, 6.5%). Mortality, morbidity, survival and re-intervention were analyzed.
The overall 30-day mortality rate was 8.0% (16/200). Stroke was present in 3.5% (7/200) of the general cohort and spinal cord injury was occurred in 3.0% (6/200). Multivariable logistic analysis showed that cardiac malperfusion and CPB time were the risk factors associated with 30-day mortality. The mean follow-up duration was 25.9 months (range 1-57.2 months), and the 3-year survival rate was 83.1%. On Cox regression analysis, age, diabetes, cardiac malperfusion and CPB time predicted short and mid-term overall mortality. A total of 3 patients required reintervention during the follow-up due to the thrombosis of epiaortic artificial vessels ( = 1), anastomotic leak at the site of the proximal ascending aorta ( = 1) and the type I endoleak ( = 1).
Type II HAR was performed with satisfactory early and mid-term outcomes in complex aortic arch pathologies.
杂交主动脉弓修复术(HAR)是治疗主动脉弓疾病的一种有吸引力的手术选择。目的是评估在不同的主动脉弓病变中,涉及升主动脉置换、弓部去分支和0区支架植入的II型HAR的短期和中期结果。
2016年至2019年期间纳入了200例患有累及主动脉弓的各种弥漫性主动脉病变的患者。复杂的主动脉弓疾病包括急性A型夹层(n = 129,64.5%)、急性B型夹层(n = 16,8.0%)、主动脉弓动脉瘤(n = 42,21.0%)和穿透性弓部溃疡(n = 13,6.5%)。分析死亡率、发病率、生存率和再次干预情况。
总体30天死亡率为8.0%(16/200)。在整个队列中,3.5%(7/200)的患者发生了卒中,3.0%(6/200)的患者发生了脊髓损伤。多变量逻辑分析显示,心脏灌注不良和体外循环时间是与30天死亡率相关的危险因素。平均随访时间为25.9个月(范围1 - 57.2个月),3年生存率为83.1%。Cox回归分析显示,年龄、糖尿病、心脏灌注不良和体外循环时间可预测短期和中期的总体死亡率。随访期间共有3例患者因主动脉人工血管血栓形成(n = 1)、升主动脉近端吻合口漏(n = 1)和I型内漏(n = 1)需要再次干预。
在复杂的主动脉弓病变中,II型HAR的早期和中期结果令人满意。